Synthesis of New Bis-1,2,4-Triazole Derivatives

doi:10.3390/11060469

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Molecules 2006, 11(6), 469-477; doi:10.3390/11060469

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Synthesis of New Bis-1,2,4-Triazole Derivatives

Olcay Bekircan* and Hakan Bektas

Department of Chemistry, Giresun Faculty of Arts and Sciences, Karadeniz Technical University, 28049, Giresun, Turkey

* Author to whom correspondence should be addressed.

Received: 10 May 2006; in revised form: 20 June 2006 / Accepted: 21 June 2006 / Published: 21 June 2006

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Abstract: A series of new 1,2/1,3-bis[o-(N-methylidenamino-3-aryl-5-phenyl-4H-1,2,4-triazole-4-yl)phenoxy]ethane/propane derivatives 4 were prepared in good yields bytreatment of 4-amino-3-aryl-5-phenyl-4H-1,2,4-triazoles 2 with certain bis-aldehydes 1.Compounds 4 were reduced with NaBH₄ to afford the corresponding 1,2/1,3-bis[o-(N-methylamino-3-aryl-5-phenyl-4H-1,2,4-triazole-4-yl)phenoxy]ethane/propane derivatives5. All new compounds were characterized by IR, ¹H-NMR, ¹³C-NMR and mass spectraldata.

Keywords: 4-Amino-4H-1; 2; 4-triazoles; bis-1; 2; 4-triazoles; bis-Schiff bases; bis- aldehydes

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Cite This Article

MDPI and ACS Style

Bekircan, O.; Bektas, H. Synthesis of New Bis-1,2,4-Triazole Derivatives. Molecules 2006, 11, 469-477.

AMA Style

Bekircan O, Bektas H. Synthesis of New Bis-1,2,4-Triazole Derivatives. Molecules. 2006; 11(6):469-477.

Chicago/Turabian Style

Bekircan, Olcay; Bektas, Hakan. 2006. "Synthesis of New Bis-1,2,4-Triazole Derivatives." Molecules 11, no. 6: 469-477.

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