Selective Enzymatic Reduction of Aldehydes

doi:10.3390/11050365

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Molecules 2006, 11(5), 365-369; doi:10.3390/11050365

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Selective Enzymatic Reduction of Aldehydes

Guido Sello ¹^,* , Fulvia Orsini ¹, Silvana Bernasconi ¹ and Patrizia Di Gennaro ²

¹ Dipartimento di Chimica Organica e Industriale, Università degli Studi di Milano, via Venezian 21, 20133 Milano, Italy ² Dipartimento di Scienze dell’Ambiente e del Territorio, Università di Milano-Bicocca, p.za della Scienza 1, 20126 Milano, Italy

* Author to whom correspondence should be addressed.

Received: 22 February 2006 / Accepted: 7 March 2006 / Published: 12 May 2006

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Abstract: Highly selective enzymatic reductions of aldehydes to the corresponding alcohols was performed using an E. coli JM109 whole cell biocatalyst. A selective enzymatic method for the reduction of aldehydes could provide an eco-compatible alternative to chemical methods. The simplicity, fairly wide scope and the very high observed chemoselectivity of this approach are its most unique features.

Keywords: Enzyme reaction; aldehydes; reduction; chemoselectivity.

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MDPI and ACS Style

Sello, G.; Orsini, F.; Bernasconi, S.; Di Gennaro, P. Selective Enzymatic Reduction of Aldehydes. Molecules 2006, 11, 365-369.

AMA Style

Sello G., Orsini F., Bernasconi S., Di Gennaro P. Selective Enzymatic Reduction of Aldehydes. Molecules. 2006; 11(5):365-369.

Chicago/Turabian Style

Sello, Guido; Orsini, Fulvia; Bernasconi, Silvana; Di Gennaro, Patrizia. 2006. "Selective Enzymatic Reduction of Aldehydes." Molecules 11, no. 5: 365-369.

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