Molecules 2006, 11(10), 739-750; doi:10.3390/11100739

A Simple Synthesis of 2-Thiohydantoins

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Received: 9 August 2006; in revised form: 24 August 2006 / Accepted: 24 August 2006 / Published: 2 October 2006
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: 2-Thiohydantoin derivatives are produced by heating a mixture of thiourea and an α-amino acid. The method described offers the advantages of simplicity, low cost, easy work-up and scalability.
Keywords: Amino acids; Antiviral agents; Cyclization; Heterocycles; 2-Thiohydantoin
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MDPI and ACS Style

Wang, Z.D.; Sheikh, S.O.; Zhang, Y. A Simple Synthesis of 2-Thiohydantoins. Molecules 2006, 11, 739-750.

AMA Style

Wang ZD, Sheikh SO, Zhang Y. A Simple Synthesis of 2-Thiohydantoins. Molecules. 2006; 11(10):739-750.

Chicago/Turabian Style

Wang, Zerong D.; Sheikh, Samia O.; Zhang, Yulu. 2006. "A Simple Synthesis of 2-Thiohydantoins." Molecules 11, no. 10: 739-750.

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