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Molecules 2006, 11(10), 751-757; doi:10.3390/11100751

A Simple and Cost Effective Synthesis of 3,11-Dimethylnonacosan-2-one, A Female Sex Pheromone of the German Cockroach

1
Department of Chemistry, Institute for Basic Sciences, College of Natural Sciences, Chungbuk National University, Cheongju 361–763, Chungbuk, South Korea
2
Department of Medicinal Chemistry, School of Pharmacy, University of Mississippi, P.O. Box 1848, University, Mississippi 38677–1848, USA
*
Author to whom correspondence should be addressed.
Received: 27 September 2006 / Revised: 10 October 2006 / Accepted: 10 October 2006 / Published: 12 October 2006
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Abstract

A convenient synthesis of 3,11-dimethylnonacosan-2-one (1) is described. Our strategy involves the use of well known C–alkylation and ethyl acetoacetate synthesis reactions as key steps. We expect that this method will prove to be useful for large scale preparation of 1 and modification of dimethylnonacosanones.
Keywords: 3; 11-Dimethylnonacosan-2-one; C–alkylation; Ethyl acetoacetate synthesis; Large scale preparation. 3; 11-Dimethylnonacosan-2-one; C–alkylation; Ethyl acetoacetate synthesis; Large scale preparation.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Ahn, K.; Jung, J.; Park, O. A Simple and Cost Effective Synthesis of 3,11-Dimethylnonacosan-2-one, A Female Sex Pheromone of the German Cockroach. Molecules 2006, 11, 751-757.

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