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Molecules 2006, 11(1), 59-63; doi:10.3390/11010059

Synthesis of Some New bis-Schiff Bases of Isatin and 5-Fluoroisatin in a Water Suspension Medium

*  and
Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
* Author to whom correspondence should be addressed.
Received: 27 April 2005 / Revised: 12 December 2005 / Accepted: 15 December 2005 / Published: 31 January 2006
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Condensation of aromatic primary bis-amines with isatin (1H-indole-2,3-dione) and 5-flouroisatin occurred cleanly and efficiently in a water suspension mediumwithout using any organic solvent or acid catalyst. The corresponding bis-Schiff baseswere obtained in good yields and were easily isolated by filtration. Their structures wereconfirmed by 1H-NMR, 13C-NMR, IR and mass spectra.
Keywords: bis-Schiff bases; isatn; 5-fluoroisatin bis-Schiff bases; isatn; 5-fluoroisatin
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Jarrahpour, A.A.; Khalili, D. Synthesis of Some New bis-Schiff Bases of Isatin and 5-Fluoroisatin in a Water Suspension Medium. Molecules 2006, 11, 59-63.

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