Functionalization of 6-Nitrobenzo[1,3]dioxole with Carbonyl Compounds via TDAE methodology

doi:10.3390/10030545

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Molecules 2005, 10(3), 545-551; doi:10.3390/10030545

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Functionalization of 6-Nitrobenzo[1,3]dioxole with Carbonyl Compounds via TDAE methodology

Ouassila Amiri-Attou, Thierry Terme and Patrice Vanelle*

Laboratoire de Chimie Organique Pharmaceutique, CNRS–UMR 6517, Faculté de Pharmacie, 27 Bd Jean Moulin, 13385 Marseille Cx 5, France

* Author to whom correspondence should be addressed.

Received: 31 January 2004 / Accepted: 5 February 2005 / Published: 13 May 2005

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Abstract: We report herein the synthesis of substituted 2-(6-nitrobenzo[1,3]dioxol-5-yl)-1- aryl ethanols and 2-(6-nitrobenzo[1,3]dioxol-5-yl)-propionic acid ethyl esters from the reaction of 5-chloromethyl-6-nitrobenzo[1,3]dioxole with various aromatic carbonyl and α- carbonyl ester derivatives using the tetrakis(dimethylamino)ethylene (TDAE) methodology.

Keywords: TDAE; Nitrobenzo[1; 3]dioxole; Arylethanols; Carbonyl derivatives.

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MDPI and ACS Style

Amiri-Attou, O.; Terme, T.; Vanelle, P. Functionalization of 6-Nitrobenzo[1,3]dioxole with Carbonyl Compounds via TDAE methodology. Molecules 2005, 10, 545-551.

AMA Style

Amiri-Attou O, Terme T, Vanelle P. Functionalization of 6-Nitrobenzo[1,3]dioxole with Carbonyl Compounds via TDAE methodology. Molecules. 2005; 10(3):545-551.

Chicago/Turabian Style

Amiri-Attou, Ouassila; Terme, Thierry; Vanelle, Patrice. 2005. "Functionalization of 6-Nitrobenzo[1,3]dioxole with Carbonyl Compounds via TDAE methodology." Molecules 10, no. 3: 545-551.

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