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Molecules 2005, 10(3), 545-551; doi:10.3390/10030545
Article

Functionalization of 6-Nitrobenzo[1,3]dioxole with Carbonyl Compounds via TDAE methodology

,  and *
Laboratoire de Chimie Organique Pharmaceutique, CNRS–UMR 6517, Faculté de Pharmacie, 27 Bd Jean Moulin, 13385 Marseille Cx 5, France
* Author to whom correspondence should be addressed.
Received: 31 January 2004 / Accepted: 5 February 2005 / Published: 13 May 2005
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Abstract

We report herein the synthesis of substituted 2-(6-nitrobenzo[1,3]dioxol-5-yl)-1- aryl ethanols and 2-(6-nitrobenzo[1,3]dioxol-5-yl)-propionic acid ethyl esters from the reaction of 5-chloromethyl-6-nitrobenzo[1,3]dioxole with various aromatic carbonyl and α- carbonyl ester derivatives using the tetrakis(dimethylamino)ethylene (TDAE) methodology.
Keywords: TDAE; Nitrobenzo[1; 3]dioxole; Arylethanols; Carbonyl derivatives. TDAE; Nitrobenzo[1; 3]dioxole; Arylethanols; Carbonyl derivatives.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Amiri-Attou, O.; Terme, T.; Vanelle, P. Functionalization of 6-Nitrobenzo[1,3]dioxole with Carbonyl Compounds via TDAE methodology. Molecules 2005, 10, 545-551.

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