Next Article in Journal
Investigations on the Formation of 4-Aminobicyclo[2.2.2]-octanones
Previous Article in Journal
Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues
Molecules 2005, 10(3), 516-520; doi:10.3390/10030516
Article

A Novel Aromatic Iodination Method, with Sodium Periodate Used as the Only Iodinating Reagent

,  and *
Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University, Banacha 1, PL 02-097 Warsaw, Poland
* Author to whom correspondence should be addressed.
Received: 10 November 2004 / Accepted: 10 March 2005 / Published: 13 May 2005
Download PDF [79 KB, uploaded 18 June 2014]
SciFeed

Abstract

Benzene, halobenzenes and some deactivated arenes readily reacted inanhydrous NaIO4/AcOH/Ac2O/concd. H2SO4 mixtures to afford, after quenching withexcess aqueous Na2SO3 solution (a reducing agent), purified iodinated products in 27-88% yields. This novel method of aromatic iodination is simple, fairly effective andenvironmentally safe.
Keywords: Arenes; iodoarenes; aromatic iodination; sodium periodate; periodyl organic intermediates. Arenes; iodoarenes; aromatic iodination; sodium periodate; periodyl organic intermediates.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Luliński, P.; Sosnowski, M.; Skulski, L. A Novel Aromatic Iodination Method, with Sodium Periodate Used as the Only Iodinating Reagent. Molecules 2005, 10, 516-520.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert