Molecules 2005, 10(2), 508-515; doi:10.3390/10020508
Article

Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues

Received: 4 January 2005; in revised form: 9 February 2005 / Accepted: 10 February 2005 / Published: 28 February 2005
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compounds.
Keywords: Microwave; nucleophilic aromatic substitution; nucleosides.
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MDPI and ACS Style

Lanver, A.; Schmalz, H.-G. Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues. Molecules 2005, 10, 508-515.

AMA Style

Lanver A, Schmalz H-G. Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues. Molecules. 2005; 10(2):508-515.

Chicago/Turabian Style

Lanver, A.; Schmalz, H.-G. 2005. "Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues." Molecules 10, no. 2: 508-515.

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