Next Article in Journal
A Novel Aromatic Iodination Method, with Sodium Periodate Used as the Only Iodinating Reagent
Previous Article in Journal
Reaction of Nitrilimines and Nitrile Oxides with Hydrazines, Hydrazones and Oximes
Article Menu

Export Article

Open AccessArticle
Molecules 2005, 10(2), 508-515; doi:10.3390/10020508

Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues

Institut für Organische Chemie, Universität zu Köln, Germany
*
Author to whom correspondence should be addressed.
Received: 4 January 2005 / Revised: 9 February 2005 / Accepted: 10 February 2005 / Published: 28 February 2005
View Full-Text   |   Download PDF [166 KB, uploaded 18 June 2014]   |  

Abstract

An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compounds.
Keywords: Microwave; nucleophilic aromatic substitution; nucleosides. Microwave; nucleophilic aromatic substitution; nucleosides.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Lanver, A.; Schmalz, H.-G. Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues. Molecules 2005, 10, 508-515.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top