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Molecules 2005, 10(2), 508-515; doi:10.3390/10020508
Article

Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues

 and *
Received: 4 January 2005; in revised form: 9 February 2005 / Accepted: 10 February 2005 / Published: 28 February 2005
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Abstract: An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compounds.
Keywords: Microwave; nucleophilic aromatic substitution; nucleosides. Microwave; nucleophilic aromatic substitution; nucleosides.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Lanver, A.; Schmalz, H.-G. Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues. Molecules 2005, 10, 508-515.

AMA Style

Lanver A, Schmalz H-G. Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues. Molecules. 2005; 10(2):508-515.

Chicago/Turabian Style

Lanver, A.; Schmalz, H.-G. 2005. "Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues." Molecules 10, no. 2: 508-515.



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