Molecules 2005, 10(12), 1429-1437; doi:10.3390/10121429
Article

Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives

1,* email, 1, 1 and 2
Received: 10 June 2005; in revised form: 6 September 2005 / Accepted: 7 September 2005 / Published: 31 December 2005
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Novel representatives of the important group of biologically active dibenzosuberone derivatives were prepared: 3,7-dibromo-5-(dimethylaminoethyl- oxyimino)-10,11-dihydro-5H-dibenzo[a,d]cyclohepta-1,4-diene (1), 3,7-dibromo-5-(3- dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene (2) and 1,7- dibromo-5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo-[a,d]-cycloheptene (3). These compounds are potential tricyclic antidepressants (TCAs), which are still the most frequently prescribed antidepressants in many countries.
Keywords: Dibenzosuberone; tricyclic antidepressants; bromination; amitriptiline; noxiptiline
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MDPI and ACS Style

Merkas, S.; Litvic, M.; Cepanec, I.; Vinkovic, V. Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives. Molecules 2005, 10, 1429-1437.

AMA Style

Merkas S, Litvic M, Cepanec I, Vinkovic V. Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives. Molecules. 2005; 10(12):1429-1437.

Chicago/Turabian Style

Merkas, Sonja; Litvic, Mladen; Cepanec, Ivica; Vinkovic, Vladimir. 2005. "Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives." Molecules 10, no. 12: 1429-1437.

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