New Insights into Parvovirus Research

Edited by
April 2020
342 pages
  • ISBN978-3-03928-310-1 (Paperback)
  • ISBN978-3-03928-311-8 (PDF)

This book is a reprint of the Special Issue New Insights into Parvovirus Research that was published in

Biology & Life Sciences
Medicine & Pharmacology
Public Health & Healthcare
Viruses in the Parvoviridae family constitute one of the most diverse and intriguing fields of research. While they all share an ssDNA genome and a small capsid, they can differ widely in structure, genome organization and expression, virus–cell interaction, and impact on the host. Exploring such diversity and unraveling the inherent complexity in these apparently simple viruses is an ongoing endeavor and commitment for the scientific community. The translational implications of research on parvoviruses are relevant. Within the family, some viruses are important human and veterinary pathogens, in need of diagnostic methods and antiviral strategies; other viruses have long been studied and engineered as tools for oncolytic therapy, or as sophisticated gene delivery vectors, and can now display their wide and expanding applicative potential. This Special Issue of Viruses collects recent contributions in the field of parvovirus research, with a focus on new insights and research on unresolved issues, as well as new approaches exploiting systemic methodologies. Evolution, structural biology, viral replication, virus–host interaction, pathogenesis and immunity, and viral oncotherapy are a selection of the topics addressed in the issue that can be of relevance to the community involved in parvovirus research and of interest to a wider audience.
  • Paperback
© 2020 by the authors; CC BY-NC-ND license
human bocavirus; children; acute gastroenteritis; parvovirus; human bocavirus 1; RNA-seq; transcription profile; human airway epithelia; AAV2; adeno-associated virus; bisulfite PCR; CpG methylation; DNA virus; Parvoviridae; telbivudine; B19V; circulating angiogenic cells; apoptosis; caspase-3; BIRC3 (cIAP-2); parvovirus; viral metagenomics; virus diversity; virus phylogeny; agricultural pests; arthropod; mite; viral communities; viral ecology; Carnivore protoparvovirus 1; canine parvovirus; feline panleukopenia virus; NS1; NS2; sequence analysis; evolution; Bombyx mori bidensovirus; RACE; RT-qPCR; transcription mapping; overlapping promoters; parvovirus; densovirus; single stranded DNA virus; X-ray crystallography; Cryo-EM; antibody interactions; receptor interactions; parvovirus; viral metagenomics; canine chapparvovirus; Adeno-associated virus; AAV; protease; phospholipase-A2; PLA2; rodent protoparvoviruses; oncolytic activity; tumor microenvironment; immunomodulation; preclinical; clinical trials; B19V; parvovirus; uncoating; divalent cations; capsid stability; genome externalization; trafficking; nuclear targeting; equine parvovirus-hepatitis; horses; commercial horse serum; phylogeny; chapparvovirus; parvovirus evolution; endogenous viral elements; Parvoviridae; densovirus; homology modeling; new viruses; oncolytic virus immune therapy; rodent protoparvoviruses; H-1PV; combination therapies; second generation parvovirus treatments; parvovirus B19; B19V; erythrovirus; diagnosis; dilated cardiomyopathy; inflammatory cardiomyopathy; myocarditis; prognosis; parvovirus B19; erythroid progenitor cells; antiviral compounds; intravenous immunoglobulin (IVIG); hydroxyurea; cidofovir; brincidofovir; coumarin derivatives; flavonoids; alpaca; virus; Bocaparvovirus; genome; next-generation sequencing; metagenomics; parvovirus B19; adenoviral vector; cell cycle arrest; apoptosis; anti-cancer; insect; Lepidoptera; insect parvovirus; chitin; peritrophins; glycans; biocontrol; parvovirus; structural biology; genetics; oncolytic viruses; antivirals