Prospects for Schistosomiasis Elimination

Edited by
September 2019
308 pages
  • ISBN978-3-03921-357-3 (Paperback)
  • ISBN978-3-03921-358-0 (PDF)

This book is a reprint of the Special Issue Prospects for Schistosomiasis Elimination that was published in

Biology & Life Sciences
Medicine & Pharmacology
Public Health & Healthcare

Current efforts to limit the ravages of schistosomiasis are pushing the world closer to eliminating a chronic infection that has been associated with human life in the tropics since time immemorial. This notwithstanding, the disease remains a scourge for large populations in sub-Saharan Africa, Latin America, and Southeast Asia, and the main part of this book is made up by papers dealing with its current distribution, discussing ways and means to establish and implement improved control approaches. While chemotherapy limits the symptoms caused by schistosomiasis, the number of infected people will not decrease until the parasite's life cycle is interrupted. To that end, some papers focus on the intermediate snail host, which is notoriously difficult to control, while others discuss human hygiene and sanitation. The latter approach not only prevents infection through avoiding people being infected from the snail, but more importantly, also stops people infecting the snail by leaving contagious feces and urine in nature. With morbidity reduced by chemotherapy, the immediate target now is the interruption of transmission to be achieved by new tools, such as the novel chemotherapies, improved diagnostics (for humans, animals, and snails), and vaccines discussed in several of the papers. As made clear in this book, a complex infection requires new tools as well as work on many fronts, above all; however, a clear idea is needed as to how to skillfully combine the tools available and sustain implemented control activities.

  • Paperback
© 2019 by the authors; CC BY-NC-ND license
schistosomiasis; Schistosoma; vaccine; zoonosis; Asia; Africa; domestic animals; buffalo; cattle; sheep; goats; Côte d’Ivoire; coverage rate; praziquantel; preventive chemotherapy; Schistosoma haematobium; Schistosoma mansoni; schistosomiasis; diagnosis; control and elimination; DNA; polymerase chain reaction; schistosomiasis; control; elimination; Africa; operational research; goals; guidelines; schistosomiasis; vector control; snail resistance; gene drive; transgenic snail; schistosomiasis; Kato-Katz; POC-CCA; young adults; soil-transmitted helminths; n/a; Mayuge; MDA coverage; praziquantel; S. mansoni; systematic non-compliance; treatment-opportunities; Uganda; climate change; schistosomiasis; distribution; intermediate snail host; transmission; modelling; schistosomiasis; soil-transmitted-helminthiasis; mapping; preventive chemotherapy; transmission control; Gabon; Central Africa; schistosomiasis; vaccine; Sm14; FABP; Schistosoma japonicum; Oncomelania hupensis; snail; 28S ribosomal DNA; PCR; loop-mediated isothermal amplification (LAMP); pooled samples; China; schistosomiasis; elimination; praziquantel; artemether; combination therapy; phylogeography; Bulinus truncatus; planorbidae; Africa; schistosomiasis; neglected tropical diseases; WIPO Re:Search; BIO Ventures for Global Health; cross-sector collaboration; capacity-building; drug discovery; public-private partnerships; GIS; remote-sensing; satellite; international space station; ECOSTRESS; worldview; spatio-temporal epidemiology; climate change; parasite; schistosomiasis, leishmaniasis; n/a; schistosomiasis; systems epidemiology; systems thinking; complexity; neglected tropical diseases; interdisciplinarity; Schistosomiasis mansoni; Caribbean; elimination; snail control; Biomphalaria glabrata; Schistosoma mekongi; Neotricula aperta; snail; Cambodia; Lao PDR; elimination; Asia; control; elimination; epidemiology; Schistosoma japonicum; Schistosoma malayensis; Schistosoma mekongi; schistosomiasis; Schistosomiasis; Philippines; schistosomiasis elimination; S. japonicum zoonosis; bovines; schistosomiasis elimination; snail control; high-sensitivity diagnostics; chemotherapy; vaccine development; health education; sanitation