Dietary Strategies for Prevention of Geriatric Diseases and Exploring the Mechanism of Aging

This Reprint, "Dietary Strategies for Prevention of Geriatric Diseases and Exploring the Mechanism of Aging," sheds light on the underlying mechanisms related to aging and age-associated pathology, while also exploring optimal nutritional strategies for the prevention and mitigation of geriatric diseases. Through exploration of the factors influencing the cellular and molecular hallmarks of aging, and age-related degenerative diseases such as immunosenescence, dynapenia, intrinsic capacity impairments and impaired mucus barrier function, it provides valuable insights into the mechanisms related to aging. Furthermore, this reprint emphasizes the powerful role of dietary interventions to mitigate age-related diseases and dysfunction. Studies on the impact of dietary intervention strategies (e.g., diversity maintenance) as well as specific supplements and nutrients, such as methyl donor nutrients, branched-chain amino acids in association with vitamin D, medium-chain triglycerides and nutraceuticals, demonstrate significant efficacy against age-associated diseases, including cognitive impairment, sarcopenia, frailty and so on. In summary, this Reprint serves as a platform to enhance understanding of the biological factors and pathogenic mechanisms involved in aging and age-related diseases, offering meaningful insights into dietary approaches for the prevention and management of geriatric diseases.