Reprint

Nanotoxicology and Nanosafety 2.0

Edited by
August 2020
320 pages
  • ISBN978-3-03936-748-1 (Hardback)
  • ISBN978-3-03936-749-8 (PDF)

This book is a reprint of the Special Issue Nanotoxicology and Nanosafety 2.0 that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary

With the rapid development of nanotechnology, nanomaterials have been widely applied in many industrial sectors, including medicine, consumer products, and electronics. While such technology has brought benefits and convenience to our daily lives, it may also potentially threaten human health. In some cases, nanomaterials present unexpected risks to both humans and the environment. Assessments of the potential hazards associated with nanotechnology have been emerging, but substantial challenges remain, because the large number of different nanomaterials cannot be effectively evaluated in a timely manner. The development of a good strategy for a nanomaterials hazard assessment not only promotes the more widespread adoption of non-rodent or 3Rs principles, but also makes nanotoxicology testing more ethical, relevant, and cost- and time-efficient. A thorough understanding of the mechanisms by which nanomaterials perturb biological systems is critical for a more comprehensive elucidation of their nanotoxicity, and this will also facilitate the development of prevention and intervention policies against adverse outcomes induced by them. We hope that the articles included in this eBook can provide updated knowledge on nanotoxicology and nanosafety, from the point of view of both toxicology and ecotoxicology.

Format
  • Hardback
License
© 2020 by the authors; CC BY-NC-ND license
Keywords
ZnO NPs; Leydig cells; apoptosis; autophagy; oxidative stress; C70; reactive oxygen species; nanoparticle toxicity; behavior tests; phenomics; Fe3O4 nanoparticles; environmental toxicology; alternative methods; safety assessment; cell-based assay; toxicity-testing strategies; human primary cell culture; predictive nanotoxicology; zinc oxide; fate; cloud point extraction; dissolution; commercial food; intestinal absorption; nanoparticles; lead oxide; inhalation exposure; toxicity; nanoparticle uptake; ICP-MS; ToF-SIMS; aluminum; vitamin; metabolomics; polystyrene; nanoplastics; neurotoxicity; behavior test; ecotoxicity; oxidative stress; zebrafish; nano-Ag; colon cells; biological toxicity; oxidative damage; plastic products; food chain; microplastics; nanoplastics; nanoparticle; cell proliferation; transition metal oxide; cell cycle; apoptosis; nanoparticles; viability; cell proliferation; physicochemical properties; oxidative stress; caspase-3; mitochondrial membrane potential; cell cycle; apoptosis; silver nanoparticles; cytotoxicity; routes of exposure; biodistribution; nanomaterials; autophagy; alternative testing strategy; high throughput screening; tiered testing strategy; C. elegans; zebrafish and Drosophila models; zebrafish embryos; acute toxicity; silver nanoparticles; chorion pore size; lysosomal activity; apoptosis; n/a; engineered nanomaterials; environmental fate models; surface waters; ENM fate processes