Reprint
Biological Activities of Alkaloids
From Toxicology to Pharmacology
Edited by
May 2020
270 pages
- ISBN978-3-03928-927-1 (Paperback)
- ISBN978-3-03928-928-8 (PDF)
This book is a reprint of the Special Issue Biological Activities of Alkaloids: From Toxicology to Pharmacology that was published in
Biology & Life Sciences
Medicine & Pharmacology
Public Health & Healthcare
Summary
Natural products are increasingly attracting attention from both basic and applied science. Plant secondary metabolites, especially alkaloids, are receiving interest from a wide range of researchers due to their biological activity. They are produced to protect plants from diseases and herbivores. Therefore, they reveal a toxic activity that affects organisms at various levels of biological organization. A growing amount of research is proving their antimicrobial, antifungal, insecticidal, and anticancer activities. That makes them applicable in various fields from medicine, to pharmacology, veterinary, and toxicology, to crop protection. This Special Issue of Toxins, “Biological Activities of Alkaloids: From Toxicology to Pharmacology", collects 15 manuscripts describing the ecological, biological, pharmacological, and toxicological effects as well as structural and analytical aspects of plant alkaloids, their mode of action, and possible application in veterinary, medicine, and plant protection. These studies prove the potential for alkaloid application in various areas of science.
Format
- Paperback
License
© 2020 by the authors; CC BY-NC-ND license
Keywords
Arecoline; lung cancer cells; mAchR3; EGFR; SRC; FAK; dehydrocrenatidine; neuropathic pain; voltage-gated sodium channels; Solanum melongena L.; malonylated form; glycoalkaloids; secondary metabolites; solasonine; solamargine; malonyl-solamargine; acetylcholinesterase; antioxidant; Ovarian cancer; Rutidea parviflora; Palmatine; Apoptosis; chanoclavine; toxicology; subchronic feeding study; acute toxicity; endophyte; Epichloë; plant secondary metabolites; glycoalkaloids; insect heart; beetles; insect; Tenebrio molitor; Radix Aconiti Lateralis preparations; short-term and long-term usage; di-ester diterpenoid alkaloids; mono-ester diterpenoid alkaloids; biodistribution; ergot alkaloids; livestock; reproduction; isoquinoline alkaloids; antimicrobial activity; Chelidonium majus; cytotoxicity; apoptosis; sanguinarine; berberine; Chelidonium majus; Berberis thunbergii; leukemia; anticancer; natural products; alkaloids; plant secondary metabolites; β-carboline; Staphylococcus aureus; antimicrobial activity; cytotoxicity; acid-sensing ion channel subtype 1a; bisbenzylisoquinoline alkaloid; lindoldhamine; nociception; inflammation; isoquinoline alkaloids; HPLC-DAD; cytotoxic activity; Mahonia aquifolia; Meconopsis cambrica; Corydalis lutea; Dicentra spectabilis; Fumaria officinalis; Macleaya cordata; alkaloids; natural sources; anticancer; antibacterial; antiviral; antifungal; Curine; alkaloid; macrophage; neutrophil; lipopolysaccharide; n/a