Reprint

A Commemorative Issue in Honor of Professor Nick Hadjiliadis: Metal Complex Interactions with Nucleic Acids and/or DNA

Edited by
February 2019
256 pages
  • ISBN978-3-03897-511-3 (Paperback)
  • ISBN978-3-03897-512-0 (PDF)

This book is a reprint of the Special Issue A Commemorative Issue in Honor of Professor Nick Hadjiliadis: Metal Complex Interactions with Nucleic Acids and/or DNA that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary
This Special Issue of the International Journal of Molecular Science comprises a comprehensive study on “Metal Complex Interactions with Nucleic Acids and/or DNA”. This Special Issue has been inspired by the important contribution of Prof. Nick Hadjiliadis to the field of palladium or/and platinum/nucleic acid interactions. It covers a selection of recent research and review articles in the field of metal complex interactions with nucleic acids and/or DNA. Moreover, this Special Issue on "Metal Complexes Interactions with Nucleic Acids and/or DNA" provides an overview of this increasingly diverse field, presenting recent developments and the latest research with particular emphasis on metal-based drugs and metal ion toxicity.
Format
  • Paperback
License and Copyright
© 2019 by the authors; CC BY-NC-ND license
Keywords
Z-DNA; ZnTMPyP4; transient absorption spectroscopy; binding mode; bleomycin analogues; DNA interaction; double-strand breaks; genome-wide; next-generation sequencing; sequence specificity; high-affinity copper transporter; hCtr1; Sp1; cisplatin; ovarian cancers; drug-resistance; metal complexes; interaction with biomolecules; nuclease activity; cytotoxicity; toxicity; DNA; oligonucleotide; hybridization; organometallic; palladacycle; palladium; quinolinyl hydrazine; copper(II) complex; cytotoxicity; apoptosis; platinum(IV) complexes; cisplatin; kiteplatin; α-lipoic acid; DNA; mitochondria; tumor spheroids; biological inorganic chemistry; acetic acid; organotins; bio-polymer; anti-cancer activity; cell cycle; organometallic ruthenium complexes; anticancer; oligodeoxynucleotide; base/sequence selectivity; thermodynamics; LC-MS; DNA; silver; ECD; QM/MM; TDDFT; palladium(III) complexes; hematoporphyrin IX; antiproliferative activity; DNA binding and repair; HMGB-1 protein; apoptosis; i-motif; CCG repeats; trinucleotide repeat DNA; chromomycin A3; neurological disease; X-ray crystallography; nucleotide flip-out; DNA deformation; DNA; metallacarboranes; boron clusters; oligonucleotide probes; therapeutic nucleic acids; G-quadruplex; tentacle porphyrins; Zn(II) porphyrin; anti-cancer therapy; end-stacking; n/a