Reprint
O-GlcNAcylation and Cancer
Edited by
January 2022
112 pages
- ISBN 978-3-0365-3083-3 (Hardback)
- ISBN 978-3-0365-3082-6 (PDF)
This is a Reprint of the Special Issue O-GlcNAcylation and Cancer that was published in
Biology & Life Sciences
Summary
This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed.