Reprint

Nutrition and Eye Health

Edited by
January 2020
242 pages
  • ISBN978-3-03921-990-2 (Paperback)
  • ISBN978-3-03921-991-9 (PDF)

This book is a reprint of the Special Issue Nutrition and Eye Health that was published in

Medicine & Pharmacology
Public Health & Healthcare
Summary

Blindness and visual impairment impact significantly on an individual’s physical and mental well-being. Loss of vision is a global health problem, with approximately 250 million of the world’s population currently living with vision loss, of which 36 million are classified as blind. Visual impairment is more frequent in the elderly, with cataract and age-related macular degeneration (AMD) accounting for over 50% of cases globally. Oxidative stress has been strongly implicated in the pathogenesis of both conditions, and consequently the role of nutritional factors, in particular carotenoids and micronutrient antioxidants, have been investigated as possible preventative or therapeutic strategies.

Dry eye syndrome (DES) is one of the most common ophthalmic conditions in the world. DES occurs where the eye does not produce enough tears and/or the tears evaporate too quicklyleading to discomfort and varying degrees of visual disturbance. There has recently been a great deal of interest in the potential for oral or topical supplementation with essential fatty acids (EFAs), specifically omega-3 and omega-6 fatty acids, as an adjunct to conventional treatments for DES.

The objective of this Special Issue on ‘Nutrition and Eye Health’ is to publish papers describing the role of nutrition in maintaining eye health and the use of nutritional interventions to prevent or treat ocular disease. A particular (but not exclusive) emphasis will be on papers (reviews and/or clinical or experimental studies) relating to cataract, AMD and DES.

Format
  • Paperback
License
© 2019 by the authors; CC BY licence
Keywords
lutein; RR-zeaxanthin; mesozeaxanthin (RS zeaxanthin); light damage; photoreceptor degeneration; oxidative stress; endoplasmic reticulum stress; electroretinography; advanced glycation end products; chyrsin; diabetic retinopathy; endoplasmic reticulum; retinal pigment epithelium; visual cycle; cataract; phytoconstituents; lens; preclinical models; drug discovery; age-related macular degeneration; gut-retina axis; gut microbiota; dietary habits; micronutrients; fish oil; omega-3 polyunsaturated fatty acids; personalised medicine; Lactobacillus paracasei KW3110; retina; light; macrophage; saffron; Crocus Sativus L.; crocin; crocetin; supplements; anti-oxidant; anti-inflammatory; AMD; diabetes; glaucoma; retina; oxidative stress; inflammation; microvascular lesions; neoangiogenesis; polyphenols; flavonoids; carotenoids; saponins; rosmarinic acid; sinapic acid; lenses; estrogen-deficient rats; oxidative stress; reduced glutathione; omega-3; fatty acid; diet; dietary assessment; clinical survey; eye disease; dry eye; age-related macular degeneration; food frequency questionnaire; CODS; clinical practice guidelines; systematic reviews; age-related macular degeneration; nutritional supplements; diet; nutrition; AGREE II; Cucurbita argyrosperma; corneal chemical burn; angiogenesis; corneal neovascularization (CNV); vascular endothelial growth factor (VEGF); interleukin-1β (IL-1β); cyclooxigenase-2 (COX-2); nuclear factor-kappaB (NF-κB); dietary antioxidants; antioxidant supplements; lens; cataract; n/a