Keywordscrosstalk; MAPK pathway; Smad-dependent TGF-β signal transduction; model of the pathway; hepatic stellate cell; microRNA regulation; NF-κB; STAT3; TGF-β; network model; simulation; T-cell activation; CD28 costimulation; calcium; Erk; NFkB; mTOR; CD45; SHP1; mathematical model; inflammation; immune homeostasis; mathematical modeling; NF-κB; TNF-α; IL-10; systems engineering; cellular biology and engineering; kinetics; mathematical modeling; parameter estimation; sensitivity analysis; B cell signaling; signal transduction; mutant Syk; computational modeling; cell response; blood coagulation; mathematical modeling; systems biology; pharmaceutical development; cancer immunology; signal transduction; modeling; cross-talk; experimental design; clonal evolution; heterogeneity; quantitative systems pharmacology; dynamic bayesian networks; endoderm; human embryonic stem cells; network inference; signaling crosstalks; n/a
