Reprint

Porphyrin-Based Compounds: Synthesis and Application

Edited by
November 2023
298 pages
  • ISBN978-3-0365-9400-2 (Hardback)
  • ISBN978-3-0365-9401-9 (PDF)

This book is a reprint of the Special Issue Porphyrin-Based Compounds: Synthesis and Application that was published in

Chemistry & Materials Science
Medicine & Pharmacology
Summary

Porphyrins, metalloporphyrins, and their analogs are a family of macrocycles that are ubiquitous in nature, playing key roles in a myriad of biological functions, such as in plant light-harvesting (e.g., chlorophyll, a magnesium–chlorin complex), oxygen binding and transport (e.g., heme group, an iron–porphyrin complex, responsible for animal cellular respiration), and bacteria photosynthesis. The pivotal functions fulfilled by these naturally occurring porphyrinoids have motivated and inspired organic chemists to produce synthetic porphyrins and analogs in the laboratory. In recent years, a multitude of applications for porphyrins has shifted the focus from purely academic interest to industrial processes.

There is a growing recognition of the need to develop new, more selective, and environmentally friendly synthetic methods. Within this Special Issue, readers will find a collection of 16 original research papers and a comprehensive review, all dedicated to exploring the synthesis and functionalization of tetrapyrrolic macrocycles. These papers shed light on the vast potential applications of these compounds across various fields.

Format
  • Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
porphyrin; human serum albumin; spectroscopy; molecular docking; chemical-biological interactions; Spirulina maxima; chlorophyll a derivatives; photosensitizers; semisynthesis; photodynamic inactivation; array; artificial photosynthesis; building block; copper-free Sonogashira coupling; ethyne; perylene; porphyrin; solar; carboxylated pyrrolidine-fused chlorin; fluorescence; glutathione detection; porphyrin macrocycles; photodynamic therapy; theranostic agents; corroles; trans-A2B-corroles; photophysics; photobiology; asymmetrical porphyrins; human U937 monocytic cells; transmembrane potential; membrane anisotropy; sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2b); Slo1; SUR2; molecular docking; asymmetric catalysis; Diels–Alder reaction; imidazolidin-4-ones; organocatalysis; photocatalysis; porphyrins; reductive amination; porphyrins; sulfonamides; MRSA; photodynamic therapy; antimicrobial resistance; photosensitizer; singlet oxygen; potassium iodide; gram-positive bacteria; Staphylococcus aureus; porphyrins; copper-64; positron emission tomography; circular dichroism; porphyrins; chirality; chiral layers; supramolecular chirality; reflectance anisotropy spectroscopy; DFT; porphyrin; organometallic; density functionals; transition metals; green chemistry; C-H functionalization; epoxidation; iron porphyrin; oxidation catalysis; renewable aromatics; phthalocyanines; solubility; gas sensors; quartz microbalances; porphyrinoids; phenothiazine; radical cation; EPR spectroscopy; ENDOR; HYSCORE; spectroelectrochemistry; BODIPY; pyridyl; nitro; chloro; methyl ester; n/a