Reprint

Molecular Mechanisms of Synaptic Plasticity: Dynamic Changes in Neurons Functions

Edited by
August 2023
290 pages
  • ISBN978-3-0365-8715-8 (Hardback)
  • ISBN978-3-0365-8714-1 (PDF)

This book is a reprint of the Special Issue Molecular Mechanisms of Synaptic Plasticity: Dynamic Changes in Neurons Functions that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary

The human brain has hundreds of billions of neurons, and at least 7 million dendrites have been hypothesized to exist for each neuron, with over 100 trillion neuron–neuron, neuron–muscle, and neuron–endocrine cell synapses [1,2]. Our body continually receives stimuli from the outer environment, and our brain’s ability to respond to these stimuli is ensured through synaptic processes, motivating the foundations of this Special Issue.This reprint aims to underline the role of synaptic plasticity phenomena in our body and clarify the mechanism operated by neurons to guarantee these phenomena. The collection in the Issue comprises 14 papers, including 8 reviews and 6 original works, one of which is a protocol for differentiating neurons from human stem cells, and 5 are preclinical works.

Format
  • Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
autophagy; proteasome; immunoproteasome; mTOR; T-cells; glia; dopamine; glutamate; neuro-inflammation; glucocorticoids; noradrenaline; dopamine; tyrosine hydroxylase; reticular formation; dopamine transporter; Parkinson’s disease; PINK1; caspase-3; striatum; synaptic plasticity; long-term depression; brain networks; connectivity; synaptic plasticity; Alzheimer’s disease (AD); schizophrenia; long-term potentiation (LTP); synaptic scaling; resting state functional MRI (rs-fMRI); synaptic plasticity; long-term potentiation (LTP); synaptic scaling; brain networks; inflammation; connectivity; multiple sclerosis; resting state functional MRI (rs-fMRI); neuregulins; ErbB receptors; synaptic plasticity; LTP; LTD; hippocampus; midbrain dopamine neurons; dopamine; brain connectivity; brain development; gut-brain axis; neurodevelopmental diseases; neuronal cytoarchitecture; neuroplasticity; regulatory T cells; serotonin (5-HT); endocannabinoid system; spatial learning; hippocampus; dorsal striatum; amygdala; Circular Hole Board; AM251; mice; dystonia; striatum; D2 receptors; synapses; dopamine volume transmission; SNARE proteins; long-term potentiation; long-term depression; learning and memory; cognition; Schaffer collateral-CA1 synapses; glia; tripartite synapse; synaptic plasticity; neurovascular unit; systems biology; Glutamate; NMDA receptors; dendritic spines; synaptic plasticity; brain disorders; transmission electron microscopy; human neurons; induced neural stem cells; synapse; synaptic vesicles; high contrast; synaptic plasticity; inhibition; computational neuroscience; GABA; LTP; LTD; n/a