Reprint

Neurodegenerative Diseases

From Molecular Basis to Therapy

Edited by
March 2023
262 pages
  • ISBN978-3-0365-7075-4 (Hardback)
  • ISBN978-3-0365-7074-7 (PDF)

This book is a reprint of the Special Issue Neurodegenerative Diseases: From Molecular Basis to Therapy that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary

Neurodegenerative diseases (NDs) are a heterogeneous group of complex diseases characterized by neuronal loss and progressive degeneration of different areas of the nervous system. NDs represent a significant health problem worldwide, with an increasing incidence rate. Although the exact pathogenesis of NDs remains unclear, a complex interaction among genetic, epigenetic, and environmental factors has been proposed. To date, no effective therapeutics have been developed to slow, halt, or prevent any NDs. Thus, information on the molecular mechanisms underlying the pathogenesis of NDs is strongly sought after. This Special Issue collected papers discussing advances in the field of NDs.

Format
  • Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
menopause; estrogen; neurodegenerative disease; Alzheimer’s disease; IGF-1; NMDAR; Parkinson’s disease; neurodegeneration; genetics; non-coding RNAs; microbiome; mitochondria; epigenetics; biomarkers; precision medicine; EAE; glutamate receptor antagonist; excitotoxicity; oxidative stress; -SH groups; superoxide dismutase; circulating microRNA; relapsing–remitting multiple sclerosis; secondary progressive multiple sclerosis; biomarker; neuroinflammation; Rab1; GTPases; Parkinson’s disease; secretory pathway; Golgi fragmentation; autophagy; α-synuclein; LRRK2; mercury; central nervous system; proteomic; motor functions; Parkinson’s disease; neurodegeneration; rotenone; neuroinflammation; dopamine; dopamine-D3-receptor; buspirone; chicoric acid; Parkinson’s disease; neuroinflammation; neurodegeneration; peripheral immune system; spleen; gut; 6-hydroxydopamine; apoptosis; mitochondrial membrane potential; neurodegenerative diseases; oxidative stress; cell culture techniques; neurodegenerative disorders; neuroprotective effect; biological products; Parkinson’s disease; striatum; caspase-3; spiny projection neurons; dendritic spines; long-term depression; Q-VD-OPh; mice; blood–brain barrier; extracellular matrix; fibronectin; liposomes; multiple sclerosis; nanomedicine; oligodendrocytes; PLGA; remyelination; therapeutic targets; n/a