Reprint

Enzyme Inhibitor from Marine Organisms

Edited by
December 2020
130 pages
  • ISBN978-3-03943-783-2 (Hardback)
  • ISBN978-3-03943-784-9 (PDF)

This book is a reprint of the Special Issue Enzyme Inhibitor from Marine Organisms that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary
Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet’s surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects.
Format
  • Hardback
License
© 2021 by the authors; CC BY-NC-ND license
Keywords
sponge Monanchora pulchra; pentacyclic guanidine alkaloids; GH36 α-galactosidase; GH109 α-N-acetylgalactosaminidase; slow-binding irreversible inhibitor; monanchomycalin B; monanhocidin A; normonanhocidin A; Alzheimer′s disease; BACE1; acetylcholinesterase; in silico docking; phlorotannins; Ulva intestinalis; ACE inhibitory peptide; optimization; purification; structural identification; molecular docking; secondary metabolites; Mycosphaerella sp.; asperchalasine; α-glucosidase; kinase inhibitors; drug development; marine natural products; inhibitor; macroalgae; marine fish; protease; Ulva ohnoi; secondary metabolites; functional annotation; structure–function relation; natural products; bioactives; enzyme inhibition; inactivation; marine bacteria; marine fungi; marine sponges