Reprint
Muscle Homeostasis and Regeneration
From Molecular Mechanisms to Therapeutic Opportunities
Edited by
November 2020
500 pages
- ISBN978-3-03943-436-7 (Hardback)
- ISBN978-3-03943-437-4 (PDF)
This book is a reprint of the Special Issue Muscle Homeostasis and Regeneration: From Molecular Mechanisms to Therapeutic Opportunities that was published in
Biology & Life Sciences
Medicine & Pharmacology
Summary
The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.
Format
- Hardback
License
© 2021 by the authors; CC BY license
Keywords
lysine; mTORC1; satellite cells; proliferation; skeletal muscle growth; muscle satellite cell; transthyretin; thyroid hormone; myogenesis; exosomes; skeletal muscle; genotype; genetic variation; muscle phenotypes; sarcopenia; aging; calcium homeostasis; hibernation; mitochondria; sarcoplasmic reticulum; skeletal muscle; Acvr1b; Tgfbr1; myostatin; Col1a1; skeletal muscle; fibrosis; myogenesis; atrophy; IGF2R; muscle homeostasis; inflammation; muscular dystrophy; pericytes; macrophages; Nfix; skeletal muscle; phagocytosis; RhoA-ROCK1; splicing isoforms; CRISPR-Cas9; exon deletion; NF-Y; muscle differentiation; C2C12 cells; sarcopenia; denervation; neuromuscular junction; heavy resistance exercise; acetylcholine receptor; cell culture; myogenesis; neonatal myosin; neural cell adhesion molecule; aging; biomarkers; mitophagy; mitochondrial dynamics; mitochondrial quality control; mitochondrial-derived vesicles (MDVs); exosomes; mitochondrial-lysosomal axis; Hibernation; electron microscopy; immunocytochemistry; α-smooth muscle actin; confocal microscopy; connexin 43; connexin 26; fibrosis; gap junctions; myofibroblasts; Platelet-Rich Plasma; skeletal muscle; transforming growth factor (TGF)-β1; muscle regeneration; inflammatory response; satellite cells; cell precursors; experimental methods; stem cell markers; muscle homeostasis; muscles; heterotopic ossification; skeletal muscle stem and progenitor cells; HO precursors; muscle atrophy; septicemia; mitochondria; mitochondrial fusion; mitochondrial fission; iPSC; extracellular vesicles; pericytes; skeletal muscle; Drosophila; muscle; genetic control; muscle diversification; muscle homeostasis; fascicle; myofiber; myofibril; sarcomere; hypertrophy; hyperplasia; splitting; radial growth; longitudinal growth; exercise; muscle regeneration; muscle stem cells; stem cells niche; muscle homeostasis; neuromuscular disorders; Duchenne muscular dystrophy; pharmacological approach; single-cell; mass cytometry; skeletal muscle regeneration; skeletal muscle homeostasis; fibro/adipogenic progenitors; myogenic progenitors; muscle populations; myogenesis; evolution; metazoans; differentiation; transdifferentiation; muscle precursors; regenerative medicine; muscle homeostasis; muscle regeneration; satellite cells; stem cells; FAPs; tissue niche; growth factors; inflammatory response; muscle pathology; aging