Ion Channels of Nociception

doi:10.3390/books978-3-03936-550-0

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Ion Channels of Nociception

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July 2020

274 pages

ISBN978-3-03936-549-4 (Hardback)
ISBN978-3-03936-550-0 (PDF)

https://doi.org/10.3390/books978-3-03936-550-0

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This book is a reprint of the Special Issue Ion Channels of Nociception that was published in

Biology & Life Sciences

Chemistry & Materials Science

Medicine & Pharmacology

Summary

The Special Issue “Ion Channels of Nociception” contains 13 articles united by a focus on the peripheral mechanisms of pain. The content covers the mechanisms of neuropathic, inflammatory, and dental pain as well as pain in migraine and diabetes; nociceptive roles of P2X3, ASIC, Piezo and TRP channels; pain control through GPCRs and pharmacological agents; and nonpharmacological treatment with electroacupuncture.

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Keywords

neuropathic pain; trigeminal system; allodynia; TRPA1; TRPV1; substance P; NK1R; nociception; anti-nociception; pain; acid-sensing ion channel (ASIC); drug action; ligand-gated ion channel; pharmacology; small molecule; nociception; ASIC3; low back pain; TRP channels; pro-inflammatory cytokines; aggrecanases; collagen; TRPA1; TRPV1; TRPV2; TRPV4; TRPC6; Elav-like; Hu proteins; diabetes; streptozotocin; thermal response; hypoalgesia; dorsal root ganglia neurons; ion channel; transient receptor potential ankyrin 1 (TRPA1); synaptic transmission; nucleus tractus solitarius (NTS); tooth pain; TRP channels; odontoblasts; piezo; purinergic; trigeminal ganglion; nociceptor; inflammatory pain; G protein-coupled receptor; voltage-gated ion channel; TRP channel; K_2P channel; Ca²⁺-activated Cl⁻ channel; migraine; animal models; experimental approaches; electroacupuncture; alleviates; inflammatory pain; DRG; SCDH; P2X3; TRPA1; TRPV1; TRPM3; ANO1; acute pain; inflammatory pain; migraine; Candidiasis; pharmacology; drug development; sodium channel; potassium channel; TRP channel; HCN channel; Piezo channels; mechanotransduction; pain; migraine; CGRP; pain; nociception; sensory neurons; ion channels; P2X3; TRPV1; TRPA1; ASIC; Piezo channels; migraine; tooth pain