Reprint
Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation
Edited by
July 2019
356 pages
- ISBN978-3-03921-265-1 (Paperback)
- ISBN978-3-03921-266-8 (PDF)
This book is a reprint of the Special Issue Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation that was published in
Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary
Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses.
Format
- Paperback
License
© 2019 by the authors; CC BY-NC-ND license
Keywords
major depressive disorder; glioblastoma; differentially expressed genes; transcriptomics; common pathway; mouse; miR-25-3p; Akt1; AP-2α; promoter; cell metabolism; p57Kip2; CDKN1C; epigenetics; disease; cell differentiation; placenta; long non-coding RNA (lncRNA); human; pregnancy; high-throughput RNA sequencing (RNA-Seq); transcriptome; Rsh regulon; Novosphingobium pentaromativorans US6-1; sphingomonads; RNA-seq; N-acyl-l-homoserine lactone; ppGpp; selenium; selenocysteine; selenoproteins; selenocysteine insertion sequence; nonsense-mediated decay; G-quadruplex; transcriptional regulation; promoter; CRISPR/Cas9; PRDM gene family; TCGA data analysis; somatic mutations; transcriptome profiling; human malignancies; tristetraprolin (TTP); tumorigenesis; posttranscriptional regulation; adenosine and uridine-rich elements (AREs); circRNA-disease associations; pathway; heterogeneous network; Patau Syndrome; cytogenetics; FOXO1; transcription factor; molecular pathways; bioinformatics; molecular docking; and drug design; transcription regulation; gene expression; causal inference; enhancer activity; insect; transcription factors; structures and functions; research methods; progress and prospects; Pax3; Pteria penguin (Röding, 1798); tyrosinase; melanin; RNA interference; liquid chromatograph-tandem mass spectrometer (LC-MS/MS); epigenetics; gene expression; nutrition; transcription; disorders; mechanisms; Crassostrea gigas; Pacific oyster; pediveliger larvae; bioadhesive; transcriptome; gene expression; interactome; microscopy; fertilization; self-incompatibility; transcriptome; tea; long non-coding RNAs; cancer; acute leukemia; therapeutic targets; Adiponectin; cancer; Adiponectin receptors; obesity; inflammatory response; inflammation; nutritional status; n/a