Reprint
Chemical Biology of Sterols, Triterpenoids and Other Natural Products
A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday
Edited by
June 2019
256 pages
- ISBN978-3-03897-416-1 (Paperback)
- ISBN978-3-03897-417-8 (PDF)
This book is a reprint of the Special Issue Chemical Biology of Sterols, Triterpenoids and Other Natural Products: A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday that was published in
Chemistry & Materials Science
Medicine & Pharmacology
Summary
Sterols and other isoprenoids are of great interest for their molecular structure and function in cell architecture and evolution, as well as for their importance in medicine and agriculture. Molecules’ 2019 Festschrift Special Issue in honor of the 65th birthday of Prof. W. David Nes, an internationally recognized chemical biologist and recipient of the George Schroepher medal for sterol research, focuses on recent developments in the chemistry, biosynthesis, and function of these polycyclic natural products. This volume of Molecules contains 16 leading-edge review articles and original research contributions from an international cast of scientists. This volume is grouped into three sections: (i) isoprenoid metabolome and diversity, (ii) clinical evaluation of sterol and triterpene structures and biosynthesis, and (iii) methods and synthesis of steroids and other compounds. The volume will be a valuable reference tool for those who study medicinal chemistry, protein chemistry, and biochemistry of isoprenoid lipids.
Format
- Paperback
License
© 2019 by the authors; CC BY-NC-ND license
Keywords
Zingiber officinale; gingerols; cytotoxic activity; oleanolic acid; high-fat high-carbohydrate diet; pre-diabetes; glucose homeostasis; insulin resistance; atherosclerosis; ROS; HUVECs; LOX-1; alkaloid; granatane; N-methylcadaverine; N-methylpiperidine. reductive deamination; Mucorales; Rhizopus arrhizus; sterol pattern; antifungal effectivity; gas chromatography-mass spectrometry (GC-MS); posaconazole; sterol biosynthesis; sterol 14α-demethylase; sterol C24-methyltransferase; mechanism-based inactivators; antifungals; azoles; antiparasitic drugs; human African trypanosomiasis; Chagas disease; synthesis; squalene cyclase; cycloartenol synthase; triterpene; fern; Polystichum; terpene; isoprenoid; divalent metal co-factor ligation; antioxidant; cholesterol; degeneration; oxysterol; retina; Smith-Lemli-Opitz syndrome; algal sterols; ergosterol biosynthesis; infectious disease; lipidomics; oxyphytosterol; pharmacognosy; phytosterol; sterolomics; lupeol; keratinocytes; fibroblasts; wound healing; cell migration; UV-radiation; ZnO; toxicity; sterol content; cholesterol; leishmania; solanaceae; withanolides; aurelianolides; phytosterols; mesocarp; oilseed; maturity; pod-blast; α-tocopherol; oil bodies; campesterol; stigmasterol; β-sitosterol; sterol; C4-demethylation complex (C4DMC); 4-methylsterol; hormone; steroid; development; genetic disease; bile alcohol; cholestanoic acid; oxysterol; sterolomics; enzyme-assisted derivatization; electrospray ionization-mass spectrometry; Girard reagent; n/a