Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Personalized Treatment of Breast Cancer submission deadline 10 Jul 2025 | 5 articles | Viewed by 8735 | Submission Open
Keywords: breast cancer treatment; oncoplastic surgery; conservative mastectomy; breast reconstruction; sentinel node biopsy; chemotherapy; radiotherapy; integrated therapies; precision medicine; personalized treatment
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Endometriosis: Updates on the Etiology, Pathophysiology, Measurements and Therapeutics submission deadline 15 Jul 2025 | 2 articles | Viewed by 9977 | Submission Open
Keywords: endometriosis; etiology; pathophysiology; measurements; therapeutics
(This special issue belongs to the Section Mechanisms of Diseases)
Advanced Minimally Invasive Surgery in Gynecology: 2nd Edition
edited by Tae-Joong Kim and
submission deadline 15 Jul 2025 | 4 articles | Viewed by 6980 | Submission Open
Keywords: minimally invasive laparoscopic surgery; ultra-minimally invasive laparoscopic surgery; single-incision laparoscopic surgery (SILS); robot-assisted laparoscopic surgery; reduced port surgery; vaginal natural orifice transluminal endoscopic surgery (vNOTES); 3D laparoscopic surgery; sentinel lymph node mapping and biopsy; tactile sensing laparoscopic surgery; augmented reality (AR) visualization laparoscopic surgery; laparoscopic ultrasound
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Clinical and Experimental Surgery in Personalized Molecular Medicine
edited by and Manousos M. Konstadoulakis
submission deadline 15 Jul 2025 | 2 articles | Viewed by 4113 | Submission Open
Keywords: personalized molecular medicine; clinical practice; surgical research; surgical oncology; multidisciplinary approaches
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Neuroscience: Molecular to Systems Approach submission deadline 15 Jul 2025 | 1 articles | Viewed by 3081 | Submission Open
Keywords: neuroscience; precision phenotyping; neuropsychiatric and neurological disorders; genomics; wearable biosensors; clinical trial
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Navigating the Evolving Landscape of Gynecology: From Diagnosis to Treatment submission deadline 15 Jul 2025 | 1 articles | Viewed by 666 | Submission Open
Keywords: gynecology; precision medicine; gynecologic oncology; women health; cancer prevention; minimally invasive gynecology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Management of Osteoarthritis Pain
edited by
submission deadline 20 Jul 2025 | 4 articles | Viewed by 16348 | Submission Open
Keywords: osteoarthritis pain; inflammation; symptoms; pathogenesis; articular cartilage; subchondral bone; diagnosis; approved treatments; future treatments; regenerative therapy; mesenchymal stem cells (MSCs); IL-1 receptor antagonists; MMP-13 inhibition; TGF-β ; Wnt/β -catenin signaling; ADAMTS-5 inhibition
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
New Advances in the Prevention and Treatment of Neurological Diseases
edited by Bruno Kusznir Vitturi
submission deadline 20 Jul 2025 | 5 articles | Viewed by 15541 | Submission Open
Keywords: neurological diseases; personalized medicine; stroke; movement disorders; dementia; epilepsy; demyelinating diseases; headaches; sleep disorders; infectious diseases of the nervous system; neuromuscular disorders
(This special issue belongs to the Section Mechanisms of Diseases)
Transforming Precision Medicine: The Intersection of Digital Health and AI—2nd Edition
edited by
submission deadline 20 Jul 2025 | 1 articles | Viewed by 2963 | Submission Open
Keywords: precision medicine; personalized medicine; genomic medicine; individualized medicine; evidence-based medicine; artificial intelligence; big data digital health
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Precision Emergency Medicine
edited by Ancor Sanz-Garcia and Francisco Martín-Rodríguez
submission deadline 25 Jul 2025 | 2 articles | Viewed by 6276 | Submission Open
Keywords: prehospital; emergency medicine; risk scores; biomarkers; emergency medical services
(This special issue belongs to the Section Personalized Critical Care)
Pharmacogenomics and Hypertension: Problems and Prospects submission deadline 25 Jul 2025 | 2 articles | Viewed by 4926 | Submission Open
Keywords: hypertension; pharmacogenomics; epigenetics; Mendelian randomization; genetic risk scores; pharmacodynamics and pharmacokinetics
(This special issue belongs to the Section Pharmacogenetics)
Challenges and New Strategies in the Management of Gliomas submission deadline 25 Jul 2025 | 1 articles | Viewed by 2124 | Submission Open
Keywords: brain tumors; human; mammals; astrocytes; microglia; oligodendroglia; neuroanatomy; neuropeptides; imaging
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Cancer Risk Assessment in Precision Medicine
edited by Agnieszka Drab
submission deadline 25 Jul 2025 | 1 articles | Viewed by 1755 | Submission Open
Keywords: cancer risk; public health; cancer epidemiology; risk factors; cancer incidence; cancer prevalence
(This special issue belongs to the Section Omics/Informatics)
Current Trends and Future Challenges in Vascular Surgery submission deadline 25 Jul 2025 | Viewed by 924 | Submission Open
Keywords: rare diseases; critical limb ischemia; carotid stenosis; artificial intelligence; aortic pathology; vascular connective disease; venous pathology; lymphatic disorder; vascular tumors; radiation safety; 3D stamping
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Innovative Research and Therapeutics in Pediatric and Adolescent and Young Adult (AYA) Oncology submission deadline 25 Jul 2025 | 1 articles | Viewed by 524 | Submission Open
Keywords: target therapy; molecular research; rare tumors; hematologic malignancies; solid tumors
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Gynecologic Oncology: Molecular Mechanisms, Diagnostics and Therapy
edited by
submission deadline 25 Jul 2025 | Viewed by 485 | Submission Open
Keywords: ultrasound; ovarian cancer; cervical cancer; endometrial cancer; uterine sarcomas; gynecologic oncology; endometriosis; ultrasound biopsy; imaging; treatment
(This special issue belongs to the Section Mechanisms of Diseases)
Skull Base Tumors: Current Status and Future Challenges submission deadline 25 Jul 2025 | Viewed by 465 | Submission Open
Keywords: skull base tumors; skull base surgery; minimally invasive surgery; molecular profiling; radiation therapy; proton therapy; chemotherapy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Risk Stratification with Diagnostic and Prognostic Relevance for Heart Failure: New Perspectives and Challenges submission deadline 25 Jul 2025 | Viewed by 303 | Submission Open
Keywords: heart failure; cardiovascular prevention; risk stratification; cardiovascular pathology; diagnostic modalities; treatment targets
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
New Perspectives and Current Challenges in Myocardial Infarction
edited by and Wojciech Wańha
submission deadline 30 Jul 2025 | 3 articles | Viewed by 4708 | Submission Open
Keywords: myocardial infarction  ; personalized medicine  ; artificial intelligence; genetics  ; targeted treatment; percutaneous coronary intervention
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Medicine for Digestive Diseases submission deadline 31 Jul 2025 | 2 articles | Viewed by 4808 | Submission Open
Keywords: colorectal cancer; esophageal cancer; gastric cancer; pancreatic cancer; liver and biliary tract cancer; biomarkers; tissue biopsy; liquid biopsy; precision medicine
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Updates and Challenges in Endoscopic and Laparoscopic Surgery
edited by Gabriella Teresa Capolupo
submission deadline 31 Jul 2025 | 2 articles | Viewed by 4404 | Submission Open
Keywords: gastrointestinal surgery; minimally invasive surgery; endoscopic surgery; endoscopic full-thickness resection; natural orifice surgery; artificial intelligence
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
AI and Precision Medicine: Innovations and Applications
edited by and Nima Pouladi
submission deadline 31 Jul 2025 | 1 articles | Viewed by 2422 | Submission Open
Keywords: artificial intelligence; precision medicine; personalized medicine; genomic medicine; personal genomics; deep learning; machine learning; generative AI; medical AI; health AI
(This special issue belongs to the Section Mechanisms of Diseases)
Orthodontics and Oral Surgery in Personalized Medicine: 2nd Edition submission deadline 31 Jul 2025 | 1 articles | Viewed by 2256 | Submission Open
Keywords: oral surgery; orthodontic; aligners; maxillo facial surgery; dental disease; dental materials; orthodontic diseases; periodontology; oral implantology; regenerative tissue; growth factor; stem cells; bone regeneration; tissue regeneration; engineering; intraoral scan; personalized medicine
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Novel Challenges and Advances in Respiratory Diseases submission deadline 31 Jul 2025 | 1 articles | Viewed by 1190 | Submission Open
Keywords: respiratory diseases; pulmonary disorders; lung health; novel therapies; diagnostic advancements; COVID-19 impact; immunotherapy; respiratory infections; airway diseases; precision medicine
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Prevention, Diagnosis and Treatment of Skin Disorders
edited by , Beata Bergler-Czop and Emanuele Cigna
submission deadline 31 Jul 2025 | 1 articles | Viewed by 851 | Submission Open
Keywords: skin disorders; skin diseases; dermatology; dermoscopy; reflectance confocal microscopy; optical coherence tomography— LC-OCT; non-melanoma skin cancer; melanoma; photodynamic therapy; raynaud phenomenon; scleroderma
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Trends and Future Development in Precision Medicine
edited by Candan Hizel
submission deadline 31 Jul 2025 | Viewed by 475 | Submission Open
Keywords: precision/personalized medicine/genomic medicine; omics disciplines; pharmacogenomics/pharmacogenetics; systems biology; bioinformatics; big data; complex diseases; rare diseases; inter-disciplinarity; public health genomics
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Minimally Invasive Thoracic Surgery: Risk Assessment and Personalized Perioperative Management
edited by and Vannucci Jacopo
submission deadline 31 Jul 2025 | Viewed by 250 | Submission Open
Keywords: VATS; ERAS; sublobar resection; risk assessment; minimally invasive thoracic surgery
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
New Insight into Aging and Geriatric Syndromes: Clinical Updates and Perspectives submission deadline 10 Aug 2025 | 5 articles | Viewed by 15162 | Submission Open
Keywords: gerodontology; dementia; mild cognitive impairment (MCI); frontotemporal dementia; frailty; late-life depression; sarcopenia; sensorial impairments; multimorbidity; oral frailty; longevity; biological aging
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Update on Robotic Gastrointestinal Surgery, 2nd Edition
edited by
submission deadline 10 Aug 2025 | 4 articles | Viewed by 12006 | Submission Open
Keywords: robotic; minimally invasive surgery; esophageal; gastric; colorectal; pancreatic; hepatic
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Treatment for Heart Failure
edited by Shunsuke Kiuchi
submission deadline 10 Aug 2025 | 1 articles | Viewed by 1555 | Submission Open
Keywords: hypertension; heart failure; prevention; left ventricular contractility; cardiovascular outcomes; cardiology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Cardiothoracic Surgery
edited by Castigliano Murthy Bhamidipati
submission deadline 15 Aug 2025 | 3 articles | Viewed by 3006 | Submission Open
Keywords: adult congenital heart disease; electrophysiology; complex aortic surgery; endocarditis; coronary artery disease; valvular heart disease
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
New Trends and Challenges in Pharmacogenomics Research
edited by
submission deadline 15 Aug 2025 | 2 articles | Viewed by 864 | Submission Open
Keywords: drug development; polygenic risk scores; diversity and inclusion; complex disease management; implementation science; genetic ancestry; special populations; rare variants
(This special issue belongs to the Section Pharmacogenetics)
Current Updates on Vascular Surgery in Personalized Medicine
edited by
submission deadline 15 Aug 2025 | Viewed by 126 | Submission Open
Keywords: carotid atherosclerosis; hematologic and radiologic biomarkers; carotid disease; plaque characterization; risk stratification
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Current Trends and Future Challenges in Assisted Reproduction
edited by
submission deadline 20 Aug 2025 | 8 articles | Viewed by 20690 | Submission Open
Keywords: infertility; fertility preservation; reproductive medicine; reproductive genetics; assisted reproduction; gynecology; andrology; embryology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Multiple Pregnancies: Optimal Follow-Up, Early Detection and Management of Complications, and Appropriate Mode and Time of Delivery submission deadline 20 Aug 2025 | 1 articles | Viewed by 1749 | Submission Open
Keywords: multiple pregnancy; twin pregnancy; triplet pregnancy; monochorionic pregnancy; monochorionic twins; monochorionic monoamniotic pregnancy; monochorionic diamniotic pregnancy; dichorionic diamniotic pregnancy; quadruplet pregnancy; chorionicity; amnionicity; conjoined twins; in vitro fertilization; assisted reproductive techniques; advanced maternal age; natural conception; pregnancy dating; aneuploidy screening; twin-to-twin transfusion syndrome (TTTS); fetal growth restriction (FGR); selective fetal growth restriction (sFGR); twin anemia-polycythemia sequence (TAPS); twin reversed arterial perfusion sequence (TRAP); fetoscopy; laser ablation; fetal laser therapy; laser therapy; bipolar cord coagulation; radiofrequency ablation; selective feticide; elective fetal reduction; elective termination of pregnancy; discordant fetal anomaly; structural abnormalities; single intrauterine fetal demise; cerclage; threatened preterm labor; preterm birth; preeclampsia; gestational hypertension; gestational diabetes; fetal ultrasound; fetal therapy; delivery; vaginal delivery; operative vaginal delivery; cesarean section; adverse perinatal outcomes
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Inborn Errors of Metabolism: From Pathomechanisms to Treatment submission deadline 20 Aug 2025 | 1 articles | Viewed by 861 | Submission Open
Keywords: inherited metabolic disorders; pathway signaling; organelle interactions; immunomodulators; antioxidants; gene therapy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Prevention and Personalized Treatment of Substance Use Disorders submission deadline 22 Aug 2025 | Viewed by 208 | Submission Open
Keywords: substance use disorder; substance dependency; biomarkers; artificial intelligence; machine learning; precision phenotyping; genomics; clinical trial
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Coronary Syndromes: Clinical Research and Personalized Medicine
edited by Miguel Nobre Menezes and Daniel Caldeira
submission deadline 25 Aug 2025 | 1 articles | Viewed by 3525 | Submission Open
Keywords: coronary artery disease; percutaneous coronary intervention; coronary artery bypass surgery; antiplatelet therapy; new and upcoming drugs for dyslipidemia; medical therapy for chronic and acute coronary syndromes; invasive and non-invasive diagnostic modalities; non-epicardial coronary artery disease; coronary artery disease in special populations (elderly; cancer; etc.); cardiovascular risk factors
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Research of Minimally Invasive Spine Surgery
edited by and Bertrand Debono
submission deadline 25 Aug 2025 | 2 articles | Viewed by 2989 | Submission Open
Keywords: minimally invasive spine surgery; MISS; surgical techniques; patient outcomes; clinical research; technological advancements; robotics; navigation systems; patient safety; quality of life
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Approaches in Neurosurgery
edited by Alessandro Boaro and Marco Mammi
submission deadline 25 Aug 2025 | 1 articles | Viewed by 2087 | Submission Open
Keywords: neurosurgery; neuronavigation; neuro-imaging; clinical outcomes; machine learning
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine for Rheumatic Diseases
edited by Rossella De Angelis, and Emilio Filippucci
submission deadline 25 Aug 2025 | 2 articles | Viewed by 1678 | Submission Open
Keywords: chronic arthritis; rheumatoid arthritis; seronegative arthritis; crystal arthropathies; connective tissue diseases; autoimmunity; laboratory medicine; ultrasound; nailfold capillaroscopy; clinimetric tools
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Gynecological Oncology: Personalized Diagnosis and Therapy
edited by Stuart Rundle and Ali Kucukmetin
submission deadline 25 Aug 2025 | 1 articles | Viewed by 1621 | Submission Open
Keywords: gynaecologic oncology; surgical oncology; medical oncology; radiation oncology; clinical oncology; palliative medicine; diagnosis; translational research; stratification; patient selection; genomics
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Therapeutic Strategies in Gastrointestinal Surgery
edited by Francesco Santullo
submission deadline 25 Aug 2025 | Viewed by 173 | Submission Open
Keywords: surgical oncology; cytoreductive surgery; laparoscopic surgery; colorectal surgery; gastric cancer; hipec; pipac; peritoneal metastases
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Diagnosis and Management of Stroke
edited by Rubens José Gagliardi
submission deadline 25 Aug 2025 | Viewed by 140 | Submission Open
Keywords: stroke; cerebrovascular disease; carotid disease; epidemiology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Therapeutic Approaches to Asthma in Clinical Medicine
edited by Howraman Meteran
submission deadline 25 Aug 2025 | Viewed by 128 | Submission Open
Keywords: asthma management; novel asthma therapies; biologic treatments for asthma; personalized medicine in asthma; monoclonal antibodies; severe asthma; precision medicine; immune-modulating therapies; gene therapy in asthma; innovative drug delivery systems; microbiome and asthma; inflammation control in asthma; asthma biomarkers; airway remodeling; corticosteroid alternatives
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Orthopaedics, 2nd Edition submission deadline 30 Aug 2025 | 7 articles | Viewed by 12907 | Submission Open
Keywords: outcomes; orthopedic surgery; traumatology; radiography; complication
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Advances in Animal Models and Precision Medicine for Cancer Research
edited by and
submission deadline 30 Aug 2025 | Viewed by 513 | Submission Open
Keywords: animal models; cancer; precision medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Prevention of Gallbladder Cancer submission deadline 31 Aug 2025 | 3 articles | Viewed by 27284 | Submission Open
Keywords: gallbladder cancer; personalized prevention; risk biomarker; primary prevention; secondary prevention/early detection; tertiary prevention/avoidance of gallbladder cancer progression
(This special issue belongs to the Section Mechanisms of Diseases)
New Perspectives, Challenges and Innovations in Modern Personalized Gynaecologic Oncology submission deadline 31 Aug 2025 | 2 articles | Viewed by 10001 | Submission Open
Keywords: gynecologic oncology; surgical oncology; medical oncology; radiation oncology; diagnosis; ethics; palliative treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Progress on Personalized Diagnosis and Treatment of Osteoarthritis submission deadline 31 Aug 2025 | 3 articles | Viewed by 8757 | Submission Open
Keywords: osteoarthritis; knee osteoarthritis; hip osteoarthritis; osteoarthritis diagnosis; osteoarthritis treatment; conservative osteoarthritis treatment; surgical osteoarthritis treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
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