Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Personalized Diagnosis and Treatment of Oligometastatic Disease
edited by
submission deadline 15 Sep 2025 | 1 articles | Viewed by 1219
Keywords: oligometastatic disease; oligorecurrence; oligoprogression; oligoconsolidation; metastasectomy; stereotactic body radiotherapy (SBRT); novel systemic agents; target therapies; chemotherapy; immunotherapy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Trauma Surgery: Strategies, Challenges and Vision of the Future
edited by and Yaniv S. Warschawski
submission deadline 20 Sep 2025 | 2 articles | Viewed by 4446 | Submission Open
Keywords: orthopaedic surgery; fractures; injuries; upper limb; trauma
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advances of Precision Medicine in Oncology submission deadline 25 Sep 2025 | 2 articles | Viewed by 7828 | Submission Open
Keywords: precision medicine; personalized cancer care; circulating tumor cells; biomolecules; liquid biopsies; omics technologies; biomarkers
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Cutting-Edge Diagnostics: The Impact of Imaging on Precision Medicine
edited by
submission deadline 25 Sep 2025 | 2 articles | Viewed by 5158 | Submission Open
Keywords: advanced imaging techniques; AI-enhanced imaging; molecular imaging; imaging biomarkers; precision medicine; personalized diagnostics; early disease detection; imaging data integration; genomics and imaging; imaging-guided interventions; clinical imaging applications; comparative imaging effectiveness; innovative imaging technologies; medical imaging advances; diagnostic accuracy; patient-specific imaging; functional imaging; quantitative imaging; radiomics; theranostics
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
The Applications of Non-Invasive Brain Stimulation in Neuropsychiatric Research and Treatment submission deadline 25 Sep 2025 | 1 articles | Viewed by 2804 | Submission Open
Keywords: neuroscience; non-invasive brain stimulation; rehabilitation; neuropsychiatric; neurophysiology; neuropsychology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Current Updates on Arrhythmia and Cardiac Electrophysiology submission deadline 25 Sep 2025 | 1 articles | Viewed by 2159 | Submission Open
Keywords: ablation energy mode; conduction system pacing; pulsed field ablation; leadless pacing; resynchronization; myocardial work; atrial fibrillation
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Advances in Interventional Radiology in Oncology
edited by
submission deadline 25 Sep 2025 | Viewed by 420 | Submission Open
Keywords: artificial intelligence; oncological imaging; hybrid imaging; endovascular radiology; percutaneous procedures; radiomics; MRI; CT; PET/CT; photon-counting CT; cone-beam CT
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Pathological Mechanism of Breast Cancer
edited by
submission deadline 25 Sep 2025 | Viewed by 397 | Submission Open
Keywords: breast cancer; metastatic breast cancer; biomarkers; molecular profiling; immune landscape; genomics; personalized treatment; targeted therapy
(This special issue belongs to the Section Mechanisms of Diseases)
Precision Medicine in Neuro-Imaging: Advances and Challenges
edited by Onur Tanglay
submission deadline 25 Sep 2025 | Viewed by 179 | Submission Open
Keywords: neuroimaging; precision medicine; biomarkers; brain health; neurotechnology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
How to Undertake Personalized Assessments and Cures for Pain
edited by Barbara Rocca and
submission deadline 30 Sep 2025 | 6 articles | Viewed by 14720 | Submission Open
Keywords: pain; suffering; personalization; evaluation; treatment; outcome; medicine; surgery; rehabilitation; psychology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Head and Neck Oncologic Surgery: Clinical Updates and New Perspectives in Precision Medicine Era
edited by Filippo Carta and Roberto Puxeddu
submission deadline 30 Sep 2025 | 4 articles | Viewed by 8722 | Submission Open
Keywords: head and neck cancer; squamous cell carcinoma; free flap; microsurgery; oral cancer; laryngeal cancer; pharyngeal cancer; skin cancer; salivary gland cancer; precision medicine; personalized medicine
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
United Airway Disease: Current Perspectives submission deadline 30 Sep 2025 | 1 articles | Viewed by 5666 | Submission Open
Keywords: chronic rhinosinusitis; asthma; personalized medicine; type-2 inflammation; united airway; obstructive sleep apnoea; monoclonal antibodies; endotype; rhinology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Updates on Heart Valve Diseases: Personalized Treatment and Management
edited by Chiara Tessari
submission deadline 30 Sep 2025 | 3 articles | Viewed by 2866 | Submission Open
Keywords: heart valve disease; congenital heart valve disease; transcatheter valve implantation/replacement; surgical technique; device technology; tissue engineering; structural valve deterioration; device failure/success
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Infectious Diseases submission deadline 30 Sep 2025 | 1 articles | Viewed by 2866 | Submission Open
Keywords: infectious diseases; genetic predisposition; post-acute infection syndromes; long-COVID; response; potential adverse events; and duration of protection of vaccines; response to therapy and development of resistance; personalized medicine; precision diagnostics; treatment strategies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Advances in Prenatal Diagnosis and Maternal Fetal Medicine submission deadline 30 Sep 2025 | 2 articles | Viewed by 1950 | Submission Open
Keywords: prenatal diagnosis; maternal– fetal medicine; fetal anomalies; genetic screening; fetal imaging; non-invasive prenatal testing (NIPT); obstetric care; perinatal outcomes; diagnostic technologies; artificial intelligence
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
New Progress in Prevention and Personalized Treatment for Cardiovascular Diseases submission deadline 30 Sep 2025 | 1 articles | Viewed by 1719 | Submission Open
Keywords: vascular medicine; hypertension; heart failure; multimorbidity; lifestyle changes; venous thromboembolic disease (VTE); cardiovascular risk; chronic coronary artery disease; cardiovascular therapy; atherosclerosis; systemic inflammation
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Clinical Advances in Neurooncology and Personalized Neurosurgery
edited by Csaba Zsolt Oláh and László Sipos
submission deadline 30 Sep 2025 | Viewed by 197 | Submission Open
Keywords: neuro-oncology; brain surgery; spine surgery; surgical techniques; quality of life; patient outcomes; interdisciplinary treatment; artificial intelligence; cutting-edge oncological treatments; radiotherapy; radiosurgery; microbiome aneurysm; perimesencephalic subarachnoid hemorrhage; COVID; microbiome; brain abscess; bacterium; fungi
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Reproduction and Fertility
edited by Nikos K. Nikolettos
submission deadline 10 Oct 2025 | Viewed by 302 | Submission Open
Keywords: personalized medicine; fertility; assisted reproduction; reproductive health
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Exploiting Metabolic Weaknesses: A Novel Approach to Overcome Drug Resistance in Cancer Therapy
edited by
submission deadline 15 Oct 2025 | 1 articles | Viewed by 3431 | Submission Open
Keywords: drug resistance; tumor metabolism; immunometabolism; metabolomics; metabolites; precision medicine
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Dermatology: Molecular Mechanisms, Diagnosis and Therapeutic Targets submission deadline 15 Oct 2025 | 2 articles | Viewed by 3316 | Submission Open
Keywords: dermatologic diseases; atopic dermatitis; psoriasis; hidradenitis suppurativa; vitiligo; alopecia; melanoma; scleroderma
(This special issue belongs to the Section Molecular Targeted Therapy)
Novel Applications of Artificial Intelligence in Personalized Medicine
edited by Aikaterini Sakagianni
submission deadline 15 Oct 2025 | 1 articles | Viewed by 1029 | Submission Open
Keywords: artificial intelligence  ; personalized medicine  ; predictive modeling  ; genomics  ; proteomics  ; AI-driven diagnostics  ; patient-specific treatment  ; drug discovery  ; healthcare innovation  ; clinical applications of AI
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Multiple Biomarkers for the Diagnosis and Precision Treatment of Depression
edited by
submission deadline 15 Oct 2025 | Viewed by 510 | Submission Open
Keywords: depression; biomarkers; inflammation; autoimmunity; genomics; physiology; radiography
(This special issue belongs to the Section Disease Biomarkers)
Gestational Diabetes: Challenges and Cutting-Edge Research submission deadline 15 Oct 2025 | Viewed by 172 | Submission Open
Keywords: gestational diabetes; continuous glucose monitor; fetal health; pregnancy; macrosomia; personalized management
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in Otolaryngology: Novel Prognostic Markers
edited by and Wolf-Dieter Baumgartner
submission deadline 20 Oct 2025 | 5 articles | Viewed by 9944 | Submission Open
Keywords: personalized medicine; otorhinolaryngology; otology; head and neck surgery; prognostic markers; individualized treatment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Hearing Disorder: Diagnosis, Implantation and Latest Research submission deadline 20 Oct 2025 | 1 articles | Viewed by 4283 | Submission Open
Keywords: hearing loss; cochlear implants; hearing preservation; neuroplasticity; outcomes in cochlear implantation; prosthesis fitting; bone-anchored hearing aids; speech perception; sound localization; gene therapy; inner-ear cell regeneration; vestibular disorders; telemedicine
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Hepato-Pancreatic-Biliary Surgery: New Perspectives in Precision Medicine Era
edited by
submission deadline 20 Oct 2025 | 1 articles | Viewed by 1733 | Submission Open
Keywords: hepato-pancreatic– biliary surgery; precision medicine; genomics; proteomics; nanotechnologies; molecular pathways; artificial intelligence; predictive modeling
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Cancer Biology and Precision Oncology
edited by Wen-Shin Chang
submission deadline 20 Oct 2025 | Viewed by 234 | Submission Open
Keywords: biomarkers; cancer genomics; diagnosis; single nucleotide polymorphism (SNP); prognosis
(This special issue belongs to the Section Disease Biomarkers)
State of the Art in Cardiac Imaging
edited by
submission deadline 25 Oct 2025 | 2 articles | Viewed by 2691 | Submission Open
Keywords: cardiology; imaging; scintigraphy; SPECT; PET; computed tomography; magnetic resonance; echocardiography; heart failure; coronary artery disease
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Interventional Cardiology: Latest Technology, Progress and Challenge
edited by Grzegorz Sobieszek and Maksymilian P. Opolski
submission deadline 25 Oct 2025 | 2 articles | Viewed by 1908 | Submission Open
Keywords: interventional cardiology; chronic total occlusions (CTO); complex and high-risk coronary interventions (CHIP); intravascular lithotripsy (IVL); structural heart interventions; heart failure interventional treatment; electrotherapy; right- and left-ventricle hemodynamic support; left-ventricle assist device (LVAD)
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Innovations and Artificial Intelligence in Interventional Radiology: A Step Towards Personalized Medicine
edited by , Giuseppe Pellegrino and Salvatore Alessio Angileri
submission deadline 25 Oct 2025 | 1 articles | Viewed by 674 | Submission Open
Keywords: interventional radiology; artificial intelligence; augmented reality
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Current Therapeutic Strategies and Future Perspectives for Infectious Diseases
edited by Duduzile Ndwandwe
submission deadline 25 Oct 2025 | Viewed by 122 | Submission Open
Keywords: infectious diseases; antimicrobial resistance; therapeutic strategies; pandemic preparedness; innovative treatments; personalized medicine; artificial intelligence in health; global health equity
(This special issue belongs to the Section Epidemiology)
State of the Art in Pathogenesis and Targeted Therapy in Chronic Obstructive Pulmonary Disease
edited by Emanuela Tudorache
submission deadline 30 Oct 2025 | Viewed by 113 | Submission Open
Keywords: COPD; effective treatments; molecular; genetic; inflammation; biomarkers for diagnosis and prognosis; personalized medicine; novel drug delivery systems; patient outcomes; clinical practice
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Innovations in Airway Diseases
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 3197 | Submission Open
Keywords: airway pathophysiology; respiratory therapeutics; novel diagnostic techniques; personalized medicine; clinical trials in airway diseases; innovative treatment strategies; molecular mechanisms; biotechnological advances; environmental impacts; advanced diagnostic tools
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in Physical Medicine and Rehabilitation: Pediatrics, Adolescents and the Elderly submission deadline 31 Oct 2025 | 1 articles | Viewed by 2338 | Submission Open
Keywords: personalized medicine; physical medicine; exercise; rehabilitation; pediatrics; adolescents; elderly
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Novel Challenges and Therapeutic Options for Digestive and Liver Diseases—2nd Edition submission deadline 31 Oct 2025 | 1 articles | Viewed by 1425 | Submission Open
Keywords: digestive disease; gastrointestinal disease; pancreas; gallbladder; liver disease; therapy; management; microbiota; drugs; diagnosis
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Precision Medicine in Neurodevelopmental Disorders: Challenges and Opportunities
edited by Song-Yu Yang, Xue-Ying He and Manfred Philipp
submission deadline 31 Oct 2025 | 1 articles | Viewed by 794 | Submission Open
Keywords: intellectual disability; inborn metabolic disorders; X-linked disorders; retarded growth; mitochondrial diseases; genetic and genomic disorders
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Developments in Cancer Biomarkers for Diagnosis and Prognosis
edited by
submission deadline 31 Oct 2025 | Viewed by 525 | Submission Open
Keywords: cancer biomarkers; diagnosis; prognosis; therapy response biomarkers; miRNA; RNA; DNA; and proteins; cell-free biomarkers; saliva; serum; and plasma; inflammation; metabolites
(This special issue belongs to the Section Disease Biomarkers)
Current Status and Future Prospects of Histopathology in Cancer Diagnosis
edited by Serena Ammendola and
submission deadline 31 Oct 2025 | Viewed by 502 | Submission Open
Keywords: histopathology; cancer diagnostics; cancer biology; prognostic markers; targeted therapy; immunohistochemistry; molecular biology; digital pathology; artificial intelligence
(This special issue belongs to the Section Mechanisms of Diseases)
Clinical Updates and Challenges of Gynecological Cancers
edited by Ottavia D’oria, and Andrea Etrusco
submission deadline 31 Oct 2025 | Viewed by 227 | Submission Open
Keywords: gynecological cancers; ovarian cancer; cervical cancer; endometrial cancer; personalized oncology; biomarkers in gynecology; immunotherapy; surgical oncology; survivorship and quality of life; genetic profiling
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Towards Personalized Medicine in Breast Cancer
edited by Eun Young Kim
submission deadline 31 Oct 2025 | Viewed by 152 | Submission Open
Keywords: personalized medicine; breast cancer; targeted therapy; immunotherapy; pharmacogenomics; biomarkers; treatment resistance; early detection
(This special issue belongs to the Section Mechanisms of Diseases)
Chronic Obstructive Pulmonary Disease (COPD): From Diagnosis and Comorbidities to Personalized Management and Palliative Care
edited by and Florin Mihaltan
submission deadline 10 Nov 2025 | 2 articles | Viewed by 14057 | Submission Open
Keywords: risk factors; systemic inflammation; phenotypes; cardio-pulmonary functional assessment; comorbidities; exacerbations; treatment; rehabilitation; prognosis tools; palliative care; management
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Chemotherapy and Hematopoietic Stem Cell Transplantation
edited by
submission deadline 15 Nov 2025 | Viewed by 124 | Submission Open
Keywords: hematopoietic stem cell transplantation; chemotherapy toxicity and conditioning regimens; graft-versus-host disease (GVHD) management; immunotherapy and cellular therapies
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Ehealth, Telemedicine, and AI in the Precision Medicine Era
edited by
submission deadline 20 Nov 2025 | 4 articles | Viewed by 17520 | Submission Open
Keywords: digital health; artificial intelligence; telemedicine; telerehabilitation; E-health; precision medicine; remote monitoring; wearable devices; mobile health (mHealth); virtual health; health informatics; machine learning; predictive analytics; personalized medicine; health technology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Skin Pathophysiology and Management
edited by , Joanna Goldberg and Mahsa Babaei
submission deadline 20 Nov 2025 | 2 articles | Viewed by 6751 | Submission Open
Keywords: skin disease pathophysiology; skin disease diagnosis; skin disease treatment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Neurodegenerative Diseases: Molecular Pathology and Personalized Treatment submission deadline 20 Nov 2025 | 1 articles | Viewed by 5584 | Submission Open
Keywords: neurodegeneration; molecular pathology; precision medicine; biomarkers; personalized therapeutics
(This special issue belongs to the Section Mechanisms of Diseases)
Mechanisms of Airway Inflammation in Asthma
edited by Kathleen Haley
submission deadline 20 Nov 2025 | Viewed by 445 | Submission Open
Keywords: asthma; inflammation in asthma; targeted therapies; acute respiratory distress syndrome; chronic lung diseases; critical care
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Liquid Biopsy in Lung Cancer: Innovations in Precision Oncology submission deadline 20 Nov 2025 | Viewed by 253 | Submission Open
Keywords: liquid biopsy; lung cancer; biomarkers; diagnosis; personalized treatment
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Precision Medicine in Gynecological Endoscopy: From Personalized Diagnosis to Tailored Surgical Interventions
edited by , Dimitrios Zacharakis and
submission deadline 25 Nov 2025 | 2 articles | Viewed by 4092 | Submission Open
Keywords: gynecological endoscopy; minimally invasive and robotic surgeries; personalized gynecological care; gynecological healthcare; personalized diagnosis; genomic profiling; real-time imaging; AI algorithms; biomarker identification  
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Advances in Bariatric Surgery
edited by and Andrea Peri
submission deadline 25 Nov 2025 | 3 articles | Viewed by 3285 | Submission Open
Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; emerging procedures; early outcomes; long-term results
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Gynecology and Obstetrics submission deadline 25 Nov 2025 | 1 articles | Viewed by 2046 | Submission Open
Keywords: personalized medicine; genetic screening; risk assessment for pregnancy complications; fetal health monitoring; pharmacogenomics; hormone therapy; genetic testing for cancer risk fertility treatments; endometriosis; fibroid management; preventive care and screening
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
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