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Vision 2017, 1(1), 2; doi:10.3390/vision1010002

Comparing Macular Thickness Measurements in Patients with Diabetic Macular Edema with the Optos Spectral OCT/SLO and Heidelberg Spectralis HRA + OCT

1
Oxford Eye Hospital, University of Oxford, Oxford, Oxfordshire, OX3 9DU, UK
2
Sandwell & West Birmingham Hospitals NHS Trust, Dudley road, Birmingham, West Midlands, B18 7QH, UK
3
NHS Greater Glasgow and Clyde, 1055 Great Western Road, Glasgow, G12 0YN, UK
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Stephen J. Anderson
Received: 5 January 2016 / Revised: 17 February 2016 / Accepted: 3 March 2016 / Published: 12 April 2016
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Abstract

The aim of this study was to compare measurements of macular thickness, obtained from patients with diabetic macular edema, using two spectral-domain optical coherence tomography (SD-OCT) devices. These were the Spectralis Heidelberg Retina Angiograph + Optical Coherence Tomography (HRA + OCT) (Heidelberg Engineering), which is often considered the gold-standard for OCT measurement, and the Spectral Optical Coherence Tomography/Scanning Laser Ophthalmoscopy (OCT/SLO) (Optos plc), which can additionally perform microperimetry, a useful measure of visual function. In this prospective observational study, each eye had SD-OCT performed with both devices on the same day by the same investigator. Mean retinal thickness was calculated, and compared between the devices, for central and parafoveal zones within 3 mm of the fovea. 62 eyes were included. In the central, superior, temporal, inferior and nasal zones respectively, mean retinal thickness with Spectralis HRA+OCT was (in microns) 310, 343, 344, 332 and 340; measurements with Spectral OCT/SLO were 237, 298, 297, 289 and 290. Pearson correlations between the devices were 0.752, 0.85, 0.928, 0.839, and 0.823 (p < 0.0001). Although absolute measurements between the devices were significantly different and therefore not interchangeable, the correlation between the devices was over 75% and statistically significant in all zones. Thus, the Spectral OCT/SLO could reliably be used for SD-OCT in patients who may also require microperimetry assessment. View Full-Text
Keywords: diabetic macular edema; optical coherence tomography; retinal thickness; heidelberg spectralis; optos spectral OCT/SLO diabetic macular edema; optical coherence tomography; retinal thickness; heidelberg spectralis; optos spectral OCT/SLO
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Sachdev, A.; Edington, M.; Morjaria, R.; Chong, N.V. Comparing Macular Thickness Measurements in Patients with Diabetic Macular Edema with the Optos Spectral OCT/SLO and Heidelberg Spectralis HRA + OCT. Vision 2017, 1, 2.

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