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Non-Coding RNA 2018, 4(1), 5; https://doi.org/10.3390/ncrna4010005

miRNAtools: Advanced Training Using the miRNA Web of Knowledge

1
Department of Medical Physics, Marian Smoluchowski Institute of Physics, Jagiellonian University, 30-348 Kraków, Poland
2
Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Professor Egas Moniz, 1649-028 Lisbon, Portugal
*
Author to whom correspondence should be addressed.
Received: 24 January 2018 / Revised: 13 February 2018 / Accepted: 14 February 2018 / Published: 16 February 2018
(This article belongs to the Collection Non-Coding RNA Methods)
Full-Text   |   PDF [2804 KB, uploaded 22 February 2018]   |  

Abstract

Micro-RNAs (miRNAs) are small non-coding RNAs that act as negative regulators of the genomic output. Their intrinsic importance within cell biology and human disease is well known. Their mechanism of action based on the base pairing binding to their cognate targets have helped the development not only of many computer applications for the prediction of miRNA target recognition but also of specific applications for functional assessment and analysis. Learning about miRNA function requires practical training in the use of specific computer and web-based applications that are complementary to wet-lab studies. In order to guide the learning process about miRNAs, we have created miRNAtools (http://mirnatools.eu), a web repository of miRNA tools and tutorials. This article compiles tools with which miRNAs and their regulatory action can be analyzed and that function to collect and organize information dispersed on the web. The miRNAtools website contains a collection of tutorials that can be used by students and tutors engaged in advanced training courses. The tutorials engage in analyses of the functions of selected miRNAs, starting with their nomenclature and genomic localization and finishing with their involvement in specific cellular functions. View Full-Text
Keywords: miRNA; web tools; advanced teaching; tutorials miRNA; web tools; advanced teaching; tutorials
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Stępień, E.Ł.; Costa, M.C.; Enguita, F.J. miRNAtools: Advanced Training Using the miRNA Web of Knowledge. Non-Coding RNA 2018, 4, 5.

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