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On the Morphology of the Drosophila Heart
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J. Cardiovasc. Dev. Dis. 2016, 3(2), 18; doi:10.3390/jcdd3020018

Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart

Department of Biology, University of New Mexico, Albuquerque, NM 87131, USA
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Author to whom correspondence should be addressed.
Academic Editors: Rolf Bodmer and Georg Vogler
Received: 18 March 2016 / Revised: 5 May 2016 / Accepted: 11 May 2016 / Published: 12 May 2016
(This article belongs to the Special Issue Non-mammalian Animal Models to Study Heart Development and Disease)
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Abstract

The Drosophila cardiac tube was once thought to be a simple linear structure, however research over the past 15 years has revealed significant cellular and molecular complexity to this organ. Prior reviews have focused upon the gene regulatory networks responsible for the specification of the cardiac field and the activation of cardiac muscle structural genes. Here we focus upon highlighting the existence, function, and development of unique cell types within the dorsal vessel, and discuss their correspondence to analogous structures in the vertebrate heart. View Full-Text
Keywords: Drosophila; heart; transcription factor; inflow tract; cardiac valve; alary muscle; outflow tract; Tinman; seven-up Drosophila; heart; transcription factor; inflow tract; cardiac valve; alary muscle; outflow tract; Tinman; seven-up
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Lovato, T.L.; Cripps, R.M. Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart. J. Cardiovasc. Dev. Dis. 2016, 3, 18.

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