Next Article in Journal
On a New Solution of Fractional Differential Equation Using Complex Transform in the Unit Disk
Previous Article in Journal
Simplified, Analytically Solvable Model Problem for Non-Analog Monte Carlo Methods
Article Menu

Article Versions

Export Article

Open AccessArticle
Math. Comput. Appl. 2014, 19(2), 144-151; doi:10.3390/mca19020144

Estimation of Mucus Clearance in Pulmonary Airways by Means of a Regression Model

1
Department of Genetics and Bioengineering, Fatih University, 34500 B. Çekmece, Istanbul, Turkey
2
Department of Civil Engineering, Fatih University, 34500 B. Çekmece, Istanbul, Turkey
3
Department of Mechanical Engineering, University of Nevada Reno, Reno, NV, USA
*
Author to whom correspondence should be addressed.
Published: 1 August 2014
Download PDF [663 KB, uploaded 1 March 2016]

Abstract

In this study, a multivariate regression analysis was performed on a dataset obtained from experimental tracheal model for mucus clearance in pulmonary airways. Several simulations have been done to verify the validity of the generated regression model. In general, the clearance of mucus in the airways is achieved by the beating action of cilia inside the serous layer which is the primary means of removing inhaled particulates and airway debris from airways in healthy people. In this study, two types of mucus simulants are used in the experimental setup. Clearance distances of a teardrop shape simulant are measured for different velocities, slope angles and surfaces properties. On the obtained data by applying several genuine transformations we developed a multiple regression model that is able to predict clearance up to 86% accuracy. Simulations revealed several important data like direct relation between velocity and clearance and indirect relation between angle and clearance.
Keywords: mucus simulant; tracheal model; multivariate regression analysis; linear model; simulation mucus simulant; tracheal model; multivariate regression analysis; linear model; simulation
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Uulu, S.S.; Öz, H.R.; Karaca, F.; Evrensel, C.A. Estimation of Mucus Clearance in Pulmonary Airways by Means of a Regression Model. Math. Comput. Appl. 2014, 19, 144-151.

Show more citation formats Show less citations formats

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Math. Comput. Appl. EISSN 2297-8747 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top