Next Article in Journal
A Low-Cost Fluorescent Sensor for pCO2 Measurements
Next Article in Special Issue
Piezoresistive Chemical Sensors Based on Functionalized Hydrogels
Previous Article in Journal
The Shell Structure Effect on the Vapor Selectivity of Monolayer-Protected Gold Nanoparticle Sensors
Previous Article in Special Issue
Swelling Properties of Hydrogels Containing Phenylboronic Acids
Article Menu

Export Article

Open AccessArticle
Chemosensors 2014, 2(2), 97-107; doi:10.3390/chemosensors2020097

Chemo-Electrical Signal Transduction by Using Stimuli-Responsive Polymer Gate-Modified Field Effect Transistor

1
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan
2
Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, 1-8-14 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8308, Japan
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 8 October 2013 / Revised: 10 January 2014 / Accepted: 13 March 2014 / Published: 26 March 2014
(This article belongs to the Special Issue Hydrogel-Based Chemosensors)
View Full-Text   |   Download PDF [331 KB, uploaded 26 March 2014]   |  

Abstract

A glucose-responsive polymer brush was designed on a gold electrode and exploited as an extended gate for a field effect transistor (FET) based biosensor. A permittivity change at the gate interface due to the change in hydration upon specific binding with glucose was detectable. The rate of response was markedly enhanced compared to the previously studied cross-linked or gel-coupled electrode, owing to its kinetics involving no process of the polymer network diffusion. This finding may offer a new strategy of the FET-based biosensors effective not only for large molecules but also for electrically neutral molecules such as glucose with improved kinetics.
Keywords: field effect transistors; permittivity; Debye length; stimuli-responsive polymers field effect transistors; permittivity; Debye length; stimuli-responsive polymers
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Matsumoto, A.; Tsurui, Y.; Matsumoto, H.; Maeda, Y.; Hoshi, T.; Sawaguchi, T.; Miyahara, Y. Chemo-Electrical Signal Transduction by Using Stimuli-Responsive Polymer Gate-Modified Field Effect Transistor. Chemosensors 2014, 2, 97-107.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Chemosensors EISSN 2227-9040 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top