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Plants 2016, 5(2), 27; doi:10.3390/plants5020027

Flavones: From Biosynthesis to Health Benefits

1
Center for Applied Plant Sciences, The Ohio State University, Columbus, OH 43210, USA
2
Department of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA
3
Department of Physiology and Cell Biology, 305B Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Ulrike Mathesius
Received: 26 April 2016 / Revised: 15 June 2016 / Accepted: 16 June 2016 / Published: 21 June 2016
(This article belongs to the Special Issue Plant Flavonoids)
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Abstract

Flavones correspond to a flavonoid subgroup that is widely distributed in the plants, and which can be synthesized by different pathways, depending on whether they contain C- or O-glycosylation and hydroxylated B-ring. Flavones are emerging as very important specialized metabolites involved in plant signaling and defense, as well as key ingredients of the human diet, with significant health benefits. Here, we appraise flavone formation in plants, emphasizing the emerging theme that biosynthesis pathway determines flavone chemistry. Additionally, we briefly review the biological activities of flavones, both from the perspective of the functions that they play in biotic and abiotic plant interactions, as well as their roles as nutraceutical components of the human and animal diet. View Full-Text
Keywords: flavone; flavone synthase; biological activities; health benefits; cytochrome P-450; Fe2+/2-oxoglutarate-dependent dioxygenases; C-glycosyl transferases flavone; flavone synthase; biological activities; health benefits; cytochrome P-450; Fe2+/2-oxoglutarate-dependent dioxygenases; C-glycosyl transferases
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Jiang, N.; Doseff, A.I.; Grotewold, E. Flavones: From Biosynthesis to Health Benefits. Plants 2016, 5, 27.

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