Next Article in Journal
Synthesis of 1,2,3-Triazole Derivatives and Evaluation of their Anticancer Activity
Previous Article in Journal
Synthesis and Biological Evaluation of Novel Alkyl-Imidazolyl Carbinols and their Esters: Potent Antimycotics
Article Menu

Export Article

Open AccessArticle
Sci. Pharm. 2013, 81(3), 651-662; doi:10.3797/scipharm.1212-21 (registering DOI)

Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug

Chemical Research and Development Department, Aurobindo Pharma Ltd, Survey No: 71&72, Indrakaran (V), Sangareddy (M), Medak Dist., Hyderabad – 502 329, Andhra Pradesh, India
Department of Engineering Chemistry, A. U. College of Engineering (A), Andhra University, Visakhapatnam – 530 003, Andhra Pradesh, India
Author to whom correspondence should be addressed.
Received: 20 December 2012 / Accepted: 18 February 2013 / Published: 18 February 2013
Download PDF [145 KB, uploaded 28 September 2016]


Gatifloxacin is an antibacterial agent belonging to the fourth-generation fluoroquinolone family. Four piperazine-linked fluoroquinolone dimers of Gatifloxacin were observed during the laboratory process for Gatifloxacin and they were identified. The present work describes the origin, synthesis, characterization, and control of these dimers along with the synthesis of Despropylene Gatifloxacin (metabolite).
Keywords: Gatifloxacin; Piperazine dimers; Synthesis; Characterization Gatifloxacin; Piperazine dimers; Synthesis; Characterization
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

GARAGA, S.; REDDY, A.V.R.; PRABAHAR, K.J.; KORUPOLU, R.B.; SANASI, P.D. Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug. Sci. Pharm. 2013, 81, 651-662.

Show more citation formats Show less citations formats

Article Metrics

Article Access Statistics



[Return to top]
Sci. Pharm. EISSN 2218-0532 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top