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Sci. Pharm. 2009, 77(Posters (PO)), 217; doi:10.3797/scipharm.oephg.21.PO-18 (registering DOI)

Synthesis of a Building Block for Oligopeptide-Oligonucleotide Conjugates

Department of Medicinal Chemistry, University of Vienna, Althanstraße 14, 1090, Vienna, Austria
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Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
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Abstract

Antisense and siRNA oligonucleotides have been widely used in the past decade as an efficient gene-silencing tool in molecular biological investigations. However, their therapeutic application has hitherto been hampered by their poor pharmacokinetic properties.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

DIRIN, M.; WINKLER, J.; URBAN, E.; NOE, C.R. Synthesis of a Building Block for Oligopeptide-Oligonucleotide Conjugates. Sci. Pharm. 2009, 77, 217.

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