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Sci. Pharm.
Volume 77
Issue 6
10.3797/scipharm.oephg.21.SL-29
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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Abstract

Expression of Organic Anion Transporter Polypeptides (OATPs) in Human Breast Carcinoma

by
K. WLCEK
1,*,
M. SVOBODA
2,
T. THALHAMMER
2 and
W. JÄGER
1
1
Department of Clinical Pharmacy and Diagnostics, University of Vienna, Althanstraße 14, 1090, Vienna, Austria
2
Center for Physiology and Pathophysiology, Medical University of Vienna, General Hospital Vienna, Waehringerguertel 18-20, 1090, Vienna, Austria
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2009, 77(6), 196; https://doi.org/10.3797/scipharm.oephg.21.SL-29
Submission received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
Versions Notes

Excerpt

Note: In lieu of an abstract, this is an excerpt from the first page.

Organic anion transporter polypeptides (OATPs) mediate the transmembrane uptake of endogenous compounds and clinically important drugs in various tissues thereby effecting drug disposition and tissue penetration. OATPs have also been identified in gastric, pancreatic, and colon carcinomas but little is known about their expression in breast carcinoma. We therefore analyzed the expression pattern of all 11 known OATPs in three breast cancer cell lines (MCF-7, ZR-75-1, MDA-MB-231) and one immortalized breast epithelial cell line (MCF-10A) using quantitative PCR. Transcripts of 7/11 OATP genes with a remarkable heterogeneity in their expression profile were detected in control and/or cancer cell lines.[...]

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MDPI and ACS Style

WLCEK, K.; SVOBODA, M.; THALHAMMER, T.; JÄGER, W. Expression of Organic Anion Transporter Polypeptides (OATPs) in Human Breast Carcinoma. Sci. Pharm. 2009, 77, 196. https://doi.org/10.3797/scipharm.oephg.21.SL-29

AMA Style

WLCEK K, SVOBODA M, THALHAMMER T, JÄGER W. Expression of Organic Anion Transporter Polypeptides (OATPs) in Human Breast Carcinoma. Scientia Pharmaceutica. 2009; 77(Short Lectures (SL)):196. https://doi.org/10.3797/scipharm.oephg.21.SL-29

Chicago/Turabian Style

WLCEK, K., M. SVOBODA, T. THALHAMMER, and W. JÄGER. 2009. "Expression of Organic Anion Transporter Polypeptides (OATPs) in Human Breast Carcinoma" Scientia Pharmaceutica 77, Short Lectures (SL): 196. https://doi.org/10.3797/scipharm.oephg.21.SL-29

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