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Diseases 2017, 5(4), 26; https://doi.org/10.3390/diseases5040026

Pyogenic Brain Abscess Caused by Peptostreptococcus in a Patient with HIV-1 Infection

1
Division of Infectious Diseases, Department of Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA
2
Gilead Sciences, Miami, FL 33136, USA
*
Authors to whom correspondence should be addressed.
Received: 22 September 2017 / Revised: 15 November 2017 / Accepted: 15 November 2017 / Published: 17 November 2017
(This article belongs to the Section Infectious Disease)
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Abstract

In the setting of HIV, cerebral lesions are usually secondary to lymphoma and opportunistic infections; however, in patients with CD4 counts above 200 cells/uL, other pathologies such as pyogenic brain abscess could gain importance. The microbiology of pyogenic brain abscess has Staphylococcus and Streptococcus as the leading etiologic pathogens in immunocompetent individuals. Peptostreptococcus is also recognized as a common cause of brain abscess in this patient population. In HIV-infected individuals, there have been sporadic reports of Peptostreptococcus infections but none of brain abscess. We describe the case of a 43-years-old HIV-infected patient with a CD4 count of 350 cells/uL that developed a Peptostreptococcus brain abscess presumably from hematogenous spread of an odontogenic source. Treatment with stereotactic needle aspiration in two opportunities and four weeks of intravenous antibiotics led to a complete resolution of this infection. This case highlights the importance of a multidisciplinary approach for an effective treatment of pyogenic brain abscess in HIV-1 patients. View Full-Text
Keywords: pyogenic brain abscess; Peptostreptococcus; HIV; stereotactic needle aspiration pyogenic brain abscess; Peptostreptococcus; HIV; stereotactic needle aspiration
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Gonzales Zamora, J.A.; Espinoza, L.A. Pyogenic Brain Abscess Caused by Peptostreptococcus in a Patient with HIV-1 Infection. Diseases 2017, 5, 26.

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