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Diseases 2017, 5(3), 19; doi:10.3390/diseases5030019

Flavonoids and Their Metabolites: Prevention in Cardiovascular Diseases and Diabetes

1
Leicester School of Pharmacy, Faculty of Health and Life Sciences, De Montfort University, The Gateway, Leicester LE1 9BH, UK
2
Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy
These authors contributed equally to the present work.
*
Author to whom correspondence should be addressed.
Received: 2 August 2017 / Revised: 1 September 2017 / Accepted: 3 September 2017 / Published: 5 September 2017
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Abstract

The occurrence of atherosclerosis and diabetes is expanding rapidly worldwide. These two metabolic disorders often co-occur, and are part of what is often referred to as the metabolic syndrome. In order to determine future therapies, we propose that molecular mechanisms should be investigated. Once the aetiology of the metabolic syndrome is clear, a nutritional intervention should be assessed. Here we focus on the protective effects of some dietary flavonoids, and their metabolites. Further studies may also pave the way for development of novel drug candidates. View Full-Text
Keywords: antioxidants; atherosclerosis; diabetes; flavonoids; metabolites antioxidants; atherosclerosis; diabetes; flavonoids; metabolites
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Zeka, K.; Ruparelia, K.; Arroo, R.R.J.; Budriesi, R.; Micucci, M. Flavonoids and Their Metabolites: Prevention in Cardiovascular Diseases and Diabetes. Diseases 2017, 5, 19.

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