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Diseases 2016, 4(3), 27; doi:10.3390/diseases4030027

Distribution and Evolutionary History of the Mobile Genetic Element s2m in Coronaviruses

1
Norwegian Veterinary Institute, Ullevaalsveien 68, 0454 Oslo, Norway
2
Centre for Laboratory Medicine, Østfold Hospital Trust, Kalnesveien 300, 1714 Grålum, Norway
*
Author to whom correspondence should be addressed.
Academic Editor: Ding Xiang Liu
Received: 31 May 2016 / Revised: 20 July 2016 / Accepted: 25 July 2016 / Published: 28 July 2016
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Abstract

The mobile genetic element s2m has been described in several families of single-stranded RNA viruses. The function remains elusive, but an increasing number of s2m-containing sequences are being deposited in publicly available databases. Currently, more than 700 coronavirus sequences containing s2m can be found in GenBank, including the severe acute respiratory syndrome (SARS) coronavirus genome. This is an updated review of the pattern of s2m in coronaviruses, the possible functional implications and the evolutionary history. View Full-Text
Keywords: s2m; coronavirus; secondary structure; mobile genetic element s2m; coronavirus; secondary structure; mobile genetic element
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Tengs, T.; Jonassen, C.M. Distribution and Evolutionary History of the Mobile Genetic Element s2m in Coronaviruses. Diseases 2016, 4, 27.

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