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Cosmetics 2017, 4(4), 47; doi:10.3390/cosmetics4040047

New Method of Measurement of Epidermal Turnover in Humans

School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakuramachi, Hachioji City, Tokyo 192-0982, Japan
Received: 24 September 2017 / Revised: 26 October 2017 / Accepted: 7 November 2017 / Published: 10 November 2017
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Abstract

This report describes a new and simple technique to detect alterations in the rate of turnover in the epidermis without using any toxic chemical, such as a radiolabeled material. The method involves measuring the time course of the decrease of darkening of an ultraviolet A-irradiated site, compared with a non-irradiated control site. The turnover time of the persistent pigmentation on the inner side of the male forearm was 36.2 ± 6.2 days (age: 37.3 ± 11.3 years, mean ± standard deviation, n = 6), which is in reasonable agreement with the epidermal turnover time previously measured by injecting [3H] thymidine into human skin. View Full-Text
Keywords: epidermal turnover; turnover time epidermal turnover; turnover time
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Maeda, K. New Method of Measurement of Epidermal Turnover in Humans. Cosmetics 2017, 4, 47.

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