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Cosmetics 2017, 4(3), 30; doi:10.3390/cosmetics4030030

Alternative Methods to Animal Testing for the Safety Evaluation of Cosmetic Ingredients: An Overview

Departament of Biochemistry and Physiology, Faculty of Pharmacy and Food Sciences, Universitat de Barcelona, Av. Joan XXIII 27-31, Barcelona 08028, Spain
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Received: 9 August 2017 / Revised: 29 August 2017 / Accepted: 31 August 2017 / Published: 2 September 2017
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Abstract

The safety of cosmetics sold in Europe is based on the safety evaluation of each individual ingredient conducted by those responsible for putting the product on the market. However, those substances for which some concern exists with respect to human health (e.g., colorants, preservatives, UV-filters, nanomaterials) are evaluated at the European Commission level by a scientific committee, currently called the Scientific Committee on Consumer Safety (SCCS). According to the Cosmetics Regulation (European Commission, 2009), it is prohibited in the European Union (EU) to market cosmetic products and ingredients that have been tested on animals. However, the results of studies performed before the ban continue to be accepted. In the current study, we evaluated the use of in vitro methods in the dossiers submitted to the SCCS in the period between 2013 and 2016 based on the published reports issued by the scientific committee, which provides a scientific opinion on these dossiers. The results of this evaluation were compared with those of an evaluation conducted four years previously. We found that, despite a slight increase in the number of studies performed in vitro, the majority of studies submitted to the SCCS is still done principally in vivo and correspond to studies performed before the ban. View Full-Text
Keywords: alternative methods; cosmetic ingredients; safety evaluation; animal ban; dossiers; SCCS; in vitro; in vivo alternative methods; cosmetic ingredients; safety evaluation; animal ban; dossiers; SCCS; in vitro; in vivo
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Vinardell, M.P.; Mitjans, M. Alternative Methods to Animal Testing for the Safety Evaluation of Cosmetic Ingredients: An Overview. Cosmetics 2017, 4, 30.

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