Antibiotics and RNase P
AbstractRNase P is an essential endonuclease in tRNA biogenesis, which generates the mature 5′-termini of tRNAs. Most forms of RNase P are ribonucleoproteins, i.e., they consist of an essential RNA and protein subunits. The catalytic function of ribonucleoprotein RNase P enzymes resides entirely in the RNA subunit. Its high structural and functional diversity among representatives of a vast variety of phylogenetic domains indicates that RNase P could serve as a molecular target and a useful screening system for the development of new drugs in the battle against bacterial drug resistance. View Full-Text
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Drainas, D. Antibiotics and RNase P. Antibiotics 2016, 5, 15.
Drainas D. Antibiotics and RNase P. Antibiotics. 2016; 5(2):15.Chicago/Turabian Style
Drainas, Denis. 2016. "Antibiotics and RNase P." Antibiotics 5, no. 2: 15.