Next Article in Journal
Next Article in Special Issue
Previous Article in Journal
Previous Article in Special Issue
Antibiotics 2014, 3(3), 317-340; doi:10.3390/antibiotics3030317
Review

Drug Resistance Mechanisms in Mycobacterium tuberculosis

*  and
Received: 8 April 2014; in revised form: 20 June 2014 / Accepted: 23 June 2014 / Published: 2 July 2014
(This article belongs to the Special Issue Mechanisms of Antibiotic Resistance)
View Full-Text   |   Download PDF [558 KB, uploaded 2 July 2014]   |   Browse Figures
Abstract: Tuberculosis (TB) is a serious public health problem worldwide. Its situation is worsened by the presence of multidrug resistant (MDR) strains of Mycobacterium tuberculosis, the causative agent of the disease. In recent years, even more serious forms of drug resistance have been reported. A better knowledge of the mechanisms of drug resistance of M. tuberculosis and the relevant molecular mechanisms involved will improve the available techniques for rapid drug resistance detection and will help to explore new targets for drug activity and development. This review article discusses the mechanisms of action of anti-tuberculosis drugs and the molecular basis of drug resistance in M. tuberculosis.
Keywords: drug resistance; molecular mechanisms; Mycobacterium tuberculosis drug resistance; molecular mechanisms; Mycobacterium tuberculosis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Palomino, J.C.; Martin, A. Drug Resistance Mechanisms in Mycobacterium tuberculosis. Antibiotics 2014, 3, 317-340.

AMA Style

Palomino JC, Martin A. Drug Resistance Mechanisms in Mycobacterium tuberculosis. Antibiotics. 2014; 3(3):317-340.

Chicago/Turabian Style

Palomino, Juan C.; Martin, Anandi. 2014. "Drug Resistance Mechanisms in Mycobacterium tuberculosis." Antibiotics 3, no. 3: 317-340.

Antibiotics EISSN 2079-6382 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert