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Empirical Antibiotic Therapy for Ventilator-Associated Pneumonia
College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Ave., Suite 203, Memphis, TN 38632, USA
Harrison School of Pharmacy, Auburn University, 1321 Walker Building, Auburn, AL 36849, USA
* Author to whom correspondence should be addressed.
Received: 2 April 2013; in revised form: 15 June 2013 / Accepted: 18 June 2013 / Published: 4 July 2013
Abstract: Ventilator-associated pneumonia (VAP) is the most common infectious complication in the intensive care unit. It can increase duration of mechanical ventilation, length of stay, costs, and mortality. Improvements in the administration of empirical antibiotic therapy have potential to reduce the complications of VAP. This review will discuss the current data addressing empirical antibiotic therapy and the effect on mortality in patients with VAP. It will also address factors that could improve the administration of empirical antibiotics and directions for future research.
Keywords: empirical; antibiotic; ventilator-associated pneumonia
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Swanson, J.M.; Wells, D.L. Empirical Antibiotic Therapy for Ventilator-Associated Pneumonia. Antibiotics 2013, 2, 339-351.
Swanson JM, Wells DL. Empirical Antibiotic Therapy for Ventilator-Associated Pneumonia. Antibiotics. 2013; 2(3):339-351.
Swanson, Joseph M.; Wells, Diana L. 2013. "Empirical Antibiotic Therapy for Ventilator-Associated Pneumonia." Antibiotics 2, no. 3: 339-351.