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Antibiotics 2013, 2(2), 265-273; doi:10.3390/antibiotics2020265
Article

The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori

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Received: 30 March 2013 / Revised: 1 May 2013 / Accepted: 7 May 2013 / Published: 21 May 2013
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Abstract

We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in time-kill assays. Both copper-based formulations were bio-cidal against all Helicobacter pylori strains tested reducing the viable count by 4–5 log within 2 h. These two copper-based anti-microbial agents deserve further study in relation to the treatment of H. pylori-related gastric disease.
Keywords: bactericidal; copper; helicobacter; novel formulation bactericidal; copper; helicobacter; novel formulation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saracino, I.M.; Zaccaro, C.; Re, G.L.; Vaira, D.; Holton, J. The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori. Antibiotics 2013, 2, 265-273.

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