Biosensors 2013, 3(1), 58-76; doi:10.3390/bios3010058
Article

Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection

1 Université Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086 CNRS, 15 rue J-A de Baïf, 75205 Paris Cedex 13, France 2 Université Paris XI, INSERM U-1014, Groupe Hospitalier Paul Brousse-94800 Villejuif, France
* Author to whom correspondence should be addressed.
Received: 14 November 2012; in revised form: 24 December 2012 / Accepted: 10 January 2013 / Published: 14 January 2013
(This article belongs to the Special Issue Organic Electronic Bio-Devices)
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Abstract: Polyquinone derivatives are widely recognized in the literature for their remarkable properties, their biocompatibility, simple synthesis, and easy bio-functionalization. We have shown that polyquinones present very stable electroactivity in neutral aqueous medium within the cathodic potential domain avoiding side oxidation of interfering species. Besides, they can act as immobilized redox transducers for probing biomolecular interactions in sensors. Our group has been working on devices based on such modified electrodes with a view to applications for proteins, antibodies and organic pollutants using a reagentless label-free electrochemical immunosensor format. Herein, these developments are briefly reviewed and put into perspective.
Keywords: conducting polymer; square wave voltammetry; impedance spectroscopy; immunosensor; proteins; peptides; pollutants; electrochemical biosensor; label-free detection

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MDPI and ACS Style

Piro, B.; Reisberg, S.; Anquetin, G.; Duc, H.-T.; Pham, M.-C. Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection. Biosensors 2013, 3, 58-76.

AMA Style

Piro B, Reisberg S, Anquetin G, Duc H-T, Pham M-C. Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection. Biosensors. 2013; 3(1):58-76.

Chicago/Turabian Style

Piro, Benoit; Reisberg, Steeve; Anquetin, Guillaume; Duc, Huynh-Thien; Pham, Minh-Chau. 2013. "Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection." Biosensors 3, no. 1: 58-76.

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