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Nanomaterials 2016, 6(11), 211; doi:10.3390/nano6110211

Design and Electrochemical Study of Platinum-Based Nanomaterials for Sensitive Detection of Nitric Oxide in Biomedical Applications

Department of Chemistry, Lakehead University, 955 Oliver Road, Thunder Bay, ON P7B 5E1, Canada
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Author to whom correspondence should be addressed.
Academic Editors: Chen-Zhong Li and Ling-Jie Meng
Received: 21 September 2016 / Revised: 4 November 2016 / Accepted: 7 November 2016 / Published: 14 November 2016
(This article belongs to the Special Issue Nanostructured Biosensors 2016)
View Full-Text   |   Download PDF [3759 KB, uploaded 14 November 2016]   |  

Abstract

The extensive physiological and regulatory roles of nitric oxide (NO) have spurred the development of NO sensors, which are of critical importance in neuroscience and various medical applications. The development of electrochemical NO sensors is of significant importance, and has garnered a tremendous amount of attention due to their high sensitivity and selectivity, rapid response, low cost, miniaturization, and the possibility of real-time monitoring. Nanostructured platinum (Pt)-based materials have attracted considerable interest regarding their use in the design of electrochemical sensors for the detection of NO, due to their unique properties and the potential for new and innovative applications. This review focuses primarily on advances and insights into the utilization of nanostructured Pt-based electrode materials, such as nanoporous Pt, Pt and PtAu nanoparticles, PtAu nanoparticle/reduced graphene oxide (rGO), and PtW nanoparticle/rGO-ionic liquid (IL) nanocomposites, for the detection of NO. The design, fabrication, characterization, and integration of electrochemical NO sensing performance, selectivity, and durability are addressed. The attractive electrochemical properties of Pt-based nanomaterials have great potential for increasing the competitiveness of these new sensors and open up new opportunities in the creation of novel NO-sensing technologies for biological and medical applications. View Full-Text
Keywords: platinum; tungsten; nanomaterials; modified electrodes; electrocatalysis; electrochemical sensors; nitric oxide; biomedical applications platinum; tungsten; nanomaterials; modified electrodes; electrocatalysis; electrochemical sensors; nitric oxide; biomedical applications
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Govindhan, M.; Liu, Z.; Chen, A. Design and Electrochemical Study of Platinum-Based Nanomaterials for Sensitive Detection of Nitric Oxide in Biomedical Applications. Nanomaterials 2016, 6, 211.

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