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Nanomaterials 2015, 5(1), 321-350;

Hybrids of Nucleic Acids and Carbon Nanotubes for Nanobiotechnology

Biophysics Section, Department of Physics, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku, Tokyo 1628601, Japan
Academic Editor: Stephen Ralph
Received: 22 January 2015 / Revised: 25 February 2015 / Accepted: 5 March 2015 / Published: 12 March 2015
(This article belongs to the Special Issue Frontiers in Nucleic Acid Nanotechnology)
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Recent progress in the combination of nucleic acids and carbon nanotubes (CNTs) has been briefly reviewed here. Since discovering the hybridization phenomenon of DNA molecules and CNTs in 2003, a large amount of fundamental and applied research has been carried out. Among thousands of papers published since 2003, approximately 240 papers focused on biological applications were selected and categorized based on the types of nucleic acids used, but not the types of CNTs. This survey revealed that the hybridization phenomenon is strongly affected by various factors, such as DNA sequences, and for this reason, fundamental studies on the hybridization phenomenon are important. Additionally, many research groups have proposed numerous practical applications, such as nanobiosensors. The goal of this review is to provide perspective on biological applications using hybrids of nucleic acids and CNTs. View Full-Text
Keywords: single-stranded DNA; double-stranded DNA; RNA; carbon nanotubes (CNTs); functionalization single-stranded DNA; double-stranded DNA; RNA; carbon nanotubes (CNTs); functionalization

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Umemura, K. Hybrids of Nucleic Acids and Carbon Nanotubes for Nanobiotechnology. Nanomaterials 2015, 5, 321-350.

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