Nanomaterials 2012, 2(2), 92-112; doi:10.3390/nano2020092
Review

Near-Infrared Fluorescent Nanoprobes for in Vivo Optical Imaging

Chai-Hoon Quek 1 email and Kam W. Leong 1,2,* email
1 Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA 2 Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
* Author to whom correspondence should be addressed.
Received: 9 January 2012; in revised form: 23 February 2012 / Accepted: 26 March 2012 / Published: 30 March 2012
(This article belongs to the Special Issue From Molecules to Nanomaterials)
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Abstract: Near-infrared (NIR) fluorescent probes offer advantages of high photon penetration, reduced light scattering and minimal autofluorescence from living tissues, rendering them valuable for noninvasive mapping of molecular events, assessment of therapeutic efficacy, and monitoring of disease progression in animal models. This review provides an overview of the recent development of the design and optical property of the different classes of NIR fluorescent nanoprobes associated with in vivo imaging applications.
Keywords: near-infrared; in vivo imaging; fluorescent dyes; nanotechnology; nanoprobes

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Cite This Article

MDPI and ACS Style

Quek, C.-H.; Leong, K.W. Near-Infrared Fluorescent Nanoprobes for in Vivo Optical Imaging. Nanomaterials 2012, 2, 92-112.

AMA Style

Quek C-H, Leong KW. Near-Infrared Fluorescent Nanoprobes for in Vivo Optical Imaging. Nanomaterials. 2012; 2(2):92-112.

Chicago/Turabian Style

Quek, Chai-Hoon; Leong, Kam W. 2012. "Near-Infrared Fluorescent Nanoprobes for in Vivo Optical Imaging." Nanomaterials 2, no. 2: 92-112.

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