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Nanomaterials 2012, 2(2), 92-112; doi:10.3390/nano2020092

Near-Infrared Fluorescent Nanoprobes for in Vivo Optical Imaging

1
Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA
2
Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
*
Author to whom correspondence should be addressed.
Received: 9 January 2012 / Revised: 23 February 2012 / Accepted: 26 March 2012 / Published: 30 March 2012
(This article belongs to the Special Issue From Molecules to Nanomaterials)
View Full-Text   |   Download PDF [1409 KB, uploaded 30 March 2012]   |  

Abstract

Near-infrared (NIR) fluorescent probes offer advantages of high photon penetration, reduced light scattering and minimal autofluorescence from living tissues, rendering them valuable for noninvasive mapping of molecular events, assessment of therapeutic efficacy, and monitoring of disease progression in animal models. This review provides an overview of the recent development of the design and optical property of the different classes of NIR fluorescent nanoprobes associated with in vivo imaging applications.
Keywords: near-infrared; in vivo imaging; fluorescent dyes; nanotechnology; nanoprobes near-infrared; in vivo imaging; fluorescent dyes; nanotechnology; nanoprobes
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Quek, C.-H.; Leong, K.W. Near-Infrared Fluorescent Nanoprobes for in Vivo Optical Imaging. Nanomaterials 2012, 2, 92-112.

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