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Functionalized Gold Nanoparticles and Their Biomedical Applications
Center for NanoBiotechnology Research, Alabama State University, 1627, Hall Street, Montgomery, AL 36101, USA
* Author to whom correspondence should be addressed.
Received: 18 March 2011; in revised form: 3 June 2011 / Accepted: 8 June 2011 / Published: 14 June 2011
Abstract: Metal nanoparticles are being extensively used in various biomedical applications due to their small size to volume ratio and extensive thermal stability. Gold nanoparticles (GNPs) are an obvious choice due to their amenability of synthesis and functionalization, less toxicity and ease of detection. The present review focuses on various methods of functionalization of GNPs and their applications in biomedical research. Functionalization facilitates targeted delivery of these nanoparticles to various cell types, bioimaging, gene delivery, drug delivery and other therapeutic and diagnostic applications. This review is an amalgamation of recent advances in the field of functionalization of gold nanoparticles and their potential applications in the field of medicine and biology.
Keywords: gold nanoparticles; functionalization; drug delivery; gene delivery; biosensor; bioimaging
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Cite This Article
MDPI and ACS Style
Tiwari, P.M.; Vig, K.; Dennis, V.A.; Singh, S.R. Functionalized Gold Nanoparticles and Their Biomedical Applications. Nanomaterials 2011, 1, 31-63.
Tiwari PM, Vig K, Dennis VA, Singh SR. Functionalized Gold Nanoparticles and Their Biomedical Applications. Nanomaterials. 2011; 1(1):31-63.
Tiwari, Pooja M.; Vig, Komal; Dennis, Vida A.; Singh, Shree R. 2011. "Functionalized Gold Nanoparticles and Their Biomedical Applications." Nanomaterials 1, no. 1: 31-63.